New Discoveries in Biology and Molecular Markers

Approximately 25% of childhood ALL cases, and a higher proportion of adult ALL cases, lack a unifying chromosomal alteration on cytogenetic analysis. Several new subtypes of B-ALL have been recently described that exhibit distinct leukemic cell gene expression profiles, but diverse, often cytogenetically cryptic founding alterations (Figure 2).
Source: Clinical Lymphoma, Myeloma and Leukemia - Category: Hematology Authors: Source Type: research