To immunosuppress or not: Behcet & #39;s syndrome presenting as an eosinophilic pleural effusion
We present a case of clinically suspected Behcet's syndrome based on a 10-year history of recurrent multiple oral ulcers and human leukocyte antigen-B51 positivity who presented with only an EPE. Computed tomography pulmonary angiogram ruled out central thoracic vein thrombosis but was inconclusive in ruling out a subsegmental pulmonary embolism. The patient declined immunosuppressants and while on follow-up developed bilateral extensive acute lower limb deep venous thrombosis and pulmonary embolism. Upper infrarenal inferior vena cava demonstrated chronic thrombosis suggestive of its antecedent role in pulmonary embolism-related EPE during the first instance. Behcet's syndrome-related EPE can be associated with venous thromboembolism, and immunosuppressive therapy prevents the subsequent thrombotic episodes.
Source: Lung India - Category: Respiratory Medicine Authors: Shakti Kumar Bal Richa Gupta Aparna Irodi Avinash Nair John Mathew Balamugesh Thangakunam Devasahayam Jesudas Christopher Source Type: research
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