Log in to search using one of your social media accounts:

 

Advocating for Bridget: Coping with Hirschsprung ’s disease

On June 20, Bridget Landry celebrated a very special day with a hearty steak dinner. But it wasn’t her birthday. Instead, the 10-year-old and her family were marking the sixth anniversary of the day her ostomy bag was removed. As she enjoyed her meal, her parents, Carl and Laura, marveled at just how far their daughter had come. “For her first birthday, she couldn’t even take a bite of cake,” remembers Carl. Bridget’s first few months of life were similar to those of most infants: She had a typical birth, nursed and met all her milestones. Yet at six months, her parents began to notice something was amiss. She wouldn’t eat solid food, wasn’t having bowel movements and her belly looked distended. Her pediatrician suggested that she might just be constipated. “But in our heart of hearts, we knew something wasn’t right,” says Laura. A frustrating diagnosis By the time she was a year old, Bridget’s doctors in Maine had diagnosed her with Hirschsprung’s disease, a disorder in which some of the intestinal nerve cells don’t develop properly, causing them to interfere with the movement of food and stool in the intestines. Although the majority of children with Hirschsprung’s develop obstructions and other symptoms within the first six months of life, others don’t show signs of the disease for months or years. Her local surgeons treated her condition with a standard approach called a pull-throug...
Source: Thrive, Children's Hospital Boston - Category: Pediatrics Authors: Tags: Diseases & Conditions Our Patients’ Stories Center for Advanced Intestinal Rehabilitation Dr. Samuel Nurko Dr. Tom Jaksic Hirschsprung's disease Motility and Functional Gastrointestinal Disorders Center Source Type: news

Related Links:

Botulism is a potentially fatal infection characterized by progressive muscle weakness, bulbar paralysis, constipation and other autonomic dysfunctions. A recent report suggested that cancer chemotherapy might...
Source: Annals of Clinical Microbiology and Antimicrobials - Category: Microbiology Authors: Tags: Case report Source Type: research
AbstractIntroduction and hypothesisFemale pelvic organ prolapse (POP) is a common condition, with a lifetime risk for surgery of 10 –20%. Prolapse procedures are known to have a high reoperation rate. It is assumed that etiological factors for POP may also be risk factors for POP recurrence after surgery. There are few reviews available evaluating risk factors for prolapse and recurrence or recently updated meta-analysis on th is topic. Our aim was to perform a systematic review and quantitative meta-analysis to determine risk factors for prolapse recurrence after reconstructive surgery.MethodsFour electronic databas...
Source: International Urogynecology Journal - Category: OBGYN Source Type: research
Abstract The enteric nervous system (ENS) controls the function of the gastrointestinal tract and has been implicated in various diseases, including Parkinson ’s disease (PD). PD is a neurodegenerative disease with Lewy bodies (LBs) and Lewy neurites (LNs) as the main pathological features. In addition to the typical motor symptoms in PD, attention has been drawn to non-motor symptoms, such as constipation, implying dysfunction of the ENS. In the presen t study, we characterized the age-dependent morphological alterations and aggregation of α-synuclein (α-syn), the primary protein component in LBs and L...
Source: Neuroscience Bulletin - Category: Neuroscience Source Type: research
Authors: Kaneko S, Oura T, Matsui A, Shingaki T, Takeuchi M Abstract The efficacy and safety of once-weekly dulaglutide 0.75 mg (dulaglutide) compared with once-daily insulin glargine (glargine) in Japanese patients with type 2 diabetes were evaluated according to subgroups stratified by baseline glycated hemoglobin (HbA1c) (≤8.5% or>8.5%). This exploratory analysis of a randomized, open-label, phase 3 study included 361 patients. In both HbA1c subgroups (patients with baseline HbA1c ≤8.5% or>8.5%), a statistically significantly greater reduction in HbA1c was observed in dulaglutide-treated patients com...
Source: Endocrine Journal - Category: Endocrinology Tags: Endocr J Source Type: research
Authors: Mercadante S Abstract The aim of this review was to assess the role of tapentadol given at medium-high doses in opioid-tolerant patients for cancer pain management in place of step-3 analgesics. A systematic literature search was performed out of which six studies and one secondary analysis provided data regarding tapentadol used as a step- 3 analgesic for this review. Tapentadol, when used at ≥ 60 mg of oral morphine equivalents in opioid-tolerant patients with cancer pain, or passing from step-2 doses to ≥ 60 mg of oral morphine equivalents, was well tolerated and effective and could ...
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
AbstractThis review reports main progresses in various pediatric issues published in Italian Journal of Pediatrics and in international journals in 2016. New insights in clinical features or complications of several disorders may be useful for our better understanding. They comprise severe asthma, changing features of lupus erythematosus from birth to adolescence, celiac disease, functional gastrointestinal disorders, Moebius syndrome, recurrent pneumonia. Risk factors for congenital heart defects, Kawasaki disease have been widely investigated. New diagnostic tools are available for ascertaining brucellosis, celiac diseas...
Source: Italian Journal of Pediatrics - Category: Pediatrics Source Type: research
Abstract Aims/IntroductionThis phase 3, randomized, double‐blind 24‐week study with extension to 1 year assessed efficacy and safety of albiglutide compared with placebo in Japanese patients with type 2 diabetes mellitus (T2DM) inadequately controlled by diet and exercise with or without a single oral antidiabetic drug. Materials and MethodsPatients received weekly albiglutide 30 mg (n=160), albiglutide 50 mg (n=150), or placebo switched to albiglutide 30 mg after 24 weeks (n=77). Open‐label daily liraglutide 0.9 mg (n=103) was included as a reference. Oral antidiabetic drug use was discontinued before baseline. The ...
Source: Journal of Diabetes Investigation - Category: Endocrinology Authors: Tags: Original Article Source Type: research
CONSTIPATION, irritable bowel syndrome and diarrhoea are common health complaints, doctors have revealed.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Opioid-induced constipation is a common problem associated with chronic use of opioid analgesics.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Tags: Original Article Source Type: research
Publication date: Available online 14 September 2017 Source:Current Medicine Research and Practice Author(s): Amira Kamal El-Hawary, Marwa Abedel Fattah, Nirmeen Megahed, Sara Raafat, Ibrahim El-Shawaf Endometriosis is the presence of endometrial glands and stroma outside the uterine cavity and musculature and it can affect the gastrointestinal tract (GIT). Here in, we reported three cases of bowel endometriosis who presented with chronic constipation, acute intestinal obstruction and chronic abdominal pain respectively.
Source: Current Medicine Research and Practice - Category: General Medicine Source Type: research
More News: Blogging | Cardiology | Children | Constipation | Gastroenterology | Heart | Heart Transplant | Hospitals | Learning | Nasogastric Intubation | Nursing | Nutrition | Pediatrics | Rehabilitation | Universities & Medical Training