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Advocating for Bridget: Coping with Hirschsprung ’s disease

On June 20, Bridget Landry celebrated a very special day with a hearty steak dinner. But it wasn’t her birthday. Instead, the 10-year-old and her family were marking the sixth anniversary of the day her ostomy bag was removed. As she enjoyed her meal, her parents, Carl and Laura, marveled at just how far their daughter had come. “For her first birthday, she couldn’t even take a bite of cake,” remembers Carl. Bridget’s first few months of life were similar to those of most infants: She had a typical birth, nursed and met all her milestones. Yet at six months, her parents began to notice something was amiss. She wouldn’t eat solid food, wasn’t having bowel movements and her belly looked distended. Her pediatrician suggested that she might just be constipated. “But in our heart of hearts, we knew something wasn’t right,” says Laura. A frustrating diagnosis By the time she was a year old, Bridget’s doctors in Maine had diagnosed her with Hirschsprung’s disease, a disorder in which some of the intestinal nerve cells don’t develop properly, causing them to interfere with the movement of food and stool in the intestines. Although the majority of children with Hirschsprung’s develop obstructions and other symptoms within the first six months of life, others don’t show signs of the disease for months or years. Her local surgeons treated her condition with a standard approach called a pull-throug...
Source: Thrive, Children's Hospital Boston - Category: Pediatrics Authors: Tags: Diseases & Conditions Our Patients’ Stories Center for Advanced Intestinal Rehabilitation Dr. Samuel Nurko Dr. Tom Jaksic Hirschsprung's disease Motility and Functional Gastrointestinal Disorders Center Source Type: news

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Condition:   Constipation - Functional Intervention:   Other: Taking two kinds of mineral water Sponsor:   Quanta Medical Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
DIGESTION is a delicate process that could easily leave you with diarrhoea, constipation or bloating. However, taking probiotic supplements can ensure everything functions smoothly.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Publication date: February 2018 Source:Journal of Pediatric Surgery Case Reports, Volume 29 Author(s): Christian Corbin Frye, Matthew Paul Landman Giant colonic diverticula are uncommon in all age groups and are especially rare within the pediatric population, with only one known previously reported case in a child. In this case presentation, we report a rare case of a pediatric GCD, review relevant epidemiology and histology, and discuss diagnostic and treatment options. The patient was an 11-year old female with worsening chronic constipation, abdominal pain, and vomiting. CT found a large pelvic mass that was removed v...
Source: Journal of Pediatric Surgery Case Reports - Category: Surgery Source Type: research
Conclusions Anticholinergic drugs prescription was found in 10.0% of hospitalized, older patients. More than one third of these prescriptions occurred in at-risk situations and more than one in ten prescriptions induced constipation.
Source: International Journal of Clinical Pharmacy - Category: Drugs & Pharmacology Source Type: research
Abstract OBJECTIVE: To evaluate the effects of S-1, an orally administered 5-FU agent, versus taxane on patient-reported outcomes (PROs) in the SELECT BC trial. METHODS: Patients with HER2-negative and endocrine treatment-resistant breast cancer with metastasis or recurrence after surgery were randomly assigned to receive first-line taxane or S-1. PROs (secondary endpoint) were assessed using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30) and Patient Neurotoxicity Questionnaire (PNQ) at baseline and at 3, 6, and 12 months. We conducted a re...
Source: Oncology - Category: Cancer & Oncology Authors: Tags: Oncology Source Type: research
Publication date: 1 March 2018 Source:Journal of Ethnopharmacology, Volume 213 Author(s): Mansour Sobeh, Mona F. Mahmoud, Mohamed A.O. Abdelfattah, Haroan Cheng, Assem M. El-Shazly, Michael Wink Ethnopharmacological relevance Cassia abbreviata is a small to medium sized branched umbrella-shaped deciduous tree. It is widely spread in the tropics, especially in Africa, having a long history in traditional medicine for the treatment of numerous conditions such as headaches, diarrhea, constipation, some skin diseases, malaria, syphilis, pneumonia, stomach troubles, uterine pains, and against gonorrhea. Aim of the study We inv...
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
A look at the best essential oils for constipation. Included is a look at the facts of constipation and common reasons for the condition.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Complementary Medicine / Alternative Medicine Source Type: news
Abstract Chronic abdominal and pelvic pain are common, debilitating clinical conditions experienced by millions of patients around the globe. The origin of such pain commonly arises from the intestine and bladder, which share common primary roles; the collection, storage and expulsion of waste. These visceral organs are located in close proximity to one another, and also share common innervation from spinal afferent pathways. Chronic abdominal pain, constipation or diarrhoea are primary symptoms for patients with Irritable Bowel Syndrome (IBS) or Inflammatory Bowel Disease (IBD). Chronic pelvic pain, urinary urgen...
Source: Am J Physiol Gastroi... - Category: Gastroenterology Authors: Tags: Am J Physiol Gastrointest Liver Physiol Source Type: research
Conclusion and ImplicationsThe high in vitro potency and selectivity of YH12852 for 5‐HT4 receptor translated into the potent in vivo efficacy with good tolerability. YH12852 significantly improved both upper and lower bowel motility in the animal models tested, and has the potential to address considerable unmet needs in patients with functional constipation, gastroparesis or both.
Source: British Journal of Pharmacology - Category: Drugs & Pharmacology Authors: Tags: RESEARCH PAPER Source Type: research
ConclusionsThis NMA suggests that the efficacy of solifenacin 5 mg/day is at least similar to other common antimuscarinics across the spectrum of OAB symptoms analyzed, and is more effective than tolterodine 4 mg/day in reducing incontinence and UUI episodes. Solifenacin 5 mg/day has a lower risk of dry mouth compared with several agents.
Source: Neurourology and Urodynamics - Category: Urology & Nephrology Authors: Tags: ORIGINAL BASIC SCIENCE ARTICLE Source Type: research
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