An Enhanced Method of Transcutaneously Stimulating the Tibial Nerve for the Treatment of Overactive Bladder.

In this study, we propose a novel approach that combines TENS with an implanted, electrically-conductive nerve cuff to reduce the stimulation amplitude needed to activate the tibial nerve. This enhanced version of TENS (called eTENS) was designed using a computational model of the rat tibial nerve and subsequently tested in anesthetized rats. Our computational model showed that eTENS can reduce the nerve activation threshold by a factor of up to 2.6. Similar effects were also achieved by in vivo experiments (1.4 ± 0.1-fold decrease, n = 5). Among various design parameters, spatial alignment between the surface electrode and the nerve cuff was identified as an important factor. Our results show that eTENS can improve the selective activation of the rat tibial nerve, but further work is needed to evaluate its use in clinical therapies. PMID: 28849398 [PubMed - as supplied by publisher]
Source: Annals of Biomedical Engineering - Category: Biomedical Engineering Authors: Tags: Ann Biomed Eng Source Type: research

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(Natural News) Moxibustion is an age-old external treatment used in traditional Chinese medicine. It involves the burning of dried herbs like mugwort or wormwood on top of an acupuncture needle or over a layer of ginger or salt placed on the skin. Based on a bibliometric analysis on studies conducted from 1954 to 2007 in...
Source: - Category: Consumer Health News Source Type: news
Doesn’t it seem like Botox is showing up everywhere as a medical treatment? Botox is a brand of botulinum neurotoxin (BoNT), a protein substance originally derived from the bacterium Clostridium botulinum. In its original form it was the toxin responsible for botulism, the paralyzing illness often caused by eating contaminated food. BoNT is now used to treat a number of medical conditions including muscle spasms, excessive sweating, overactive bladder, and some eye muscle conditions. However, one of its most common uses is in the preventive treatment of chronic migraine. Chronic migraine, defined as headache occurrin...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Drugs and Supplements Headache Source Type: blogs
Publication date: Available online 18 September 2019Source: European UrologyAuthor(s): Bárbara Padilla-Fernández, David M. Castro-Díaz
Source: European Urology - Category: Urology & Nephrology Source Type: research
To determine if targeted and modulated radiofrequency ablation (RFA) of the urinary bladder using our novel ablation device (Denerblate) reduces bladder nerve density, potentially leading to a novel strategy for the management of overactive bladder.
Source: Urology - Category: Urology & Nephrology Authors: Source Type: research
ConclusionsClinical impression may not adequately assess frailty. Miscategorization of frailty by FPMRS providers was higher than in other fields.
Source: International Urogynecology Journal - Category: OBGYN Source Type: research
Abstract Aim: Evaluation of the executive function and working memory influence, as well as the general state of memory, on adherence to treatment with antimuscarinic drugs in elderly women with overactive bladder (OAB). Background: Antimuscarinic are effective and safe for the treatment of OAB, but adherence to treatment remains low. Demographic, socioeconomic, and medical factors which influence the medication adherence have been explored; however, the impact of executive function and working memory on adherence has not been evaluated yet. Methods: In total 417 women from 65 to 88 years old with the di...
Source: Reproductive Biology - Category: Reproduction Medicine Authors: Tags: Eur J Obstet Gynecol Reprod Biol X Source Type: research
ConclusionsAlthough men who use alpha-blockers are generally satisfied with their current therapy, most will participate in a discontinuation trial.
Source: Drugs and Aging - Category: Geriatrics Source Type: research
LUTS: Lower Urinary Tract Symptoms, Volume 11, Issue 4, Page 255-256, September 2019.
Source: LUTS: Lower Urinary Tract Symptoms - Category: Urology & Nephrology Authors: Tags: LETTER TO THE EDITOR Source Type: research
CONCLUSIONS: Despite some limitations, this study shows that the majority of patients who responded to PTNS considered themselves still improved at a seven- year follow-up. Larger studies are needed to confirm our results, but our study has the novel advantage of showing data derived from "real life" over the longest follow- up yet considered in the literature. PMID: 31487975 [PubMed - as supplied by publisher]
Source: Minerva Urologica e Nefrologica - Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
Funding Opportunity RFA-DK-19-015 from the NIH Guide for Grants and Contracts. The Prevention of Lower Urinary tract Symptoms (PLUS) Research Consortium will use qualitative and quantitative strategies to conduct collaborative, transdisciplinary studies to establish the scientific basis for future intervention studies to promote bladder health and prevent lower urinary tract symptoms (LUTS) and associated bladder conditions such as bladder infections, urinary incontinence, voiding dysfunction, overactive bladder and interstitial cystitis/bladder pain syndrome in adolescent and adult women across the life course. This FOA ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding
More News: Anesthesia | Anesthesiology | Biomedical Engineering | Overactive Bladder | Overactive Bladder Syndrome | Study | TENS