A fruitful liaison of ZSCAN10 and ROS on the road to rejuvenation

Nature Cell Biology 19, 1012 (2017).
doi:10.1038/ncb3602

Authors: Clea Bárcena & Carlos López-Otín
Induced pluripotent stem cells derived from aged donors (A-iPSCs) usually show genomic instability that affects their utility and raises concerns about their safety. Now, a study highlights the importance of ZSCAN10-dependent recovery of glutathione–ROS homeostasis in counteracting the genomic defects in A-iPSCs.

Source: Nature Cell Biology - August 31, 2017 Category: Cytology Authors: Clea B á rcena Carlos L ó pez-Ot í n Tags: News and Views Source Type: research