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A fruitful liaison of ZSCAN10 and ROS on the road to rejuvenation

Nature Cell Biology 19, 1012 (2017). doi:10.1038/ncb3602 Authors: Clea Bárcena &Carlos López-Otín Induced pluripotent stem cells derived from aged donors (A-iPSCs) usually show genomic instability that affects their utility and raises concerns about their safety. Now, a study highlights the importance of ZSCAN10-dependent recovery of glutathione–ROS homeostasis in counteracting the genomic defects in A-iPSCs.
Source: Nature Cell Biology - Category: Cytology Authors: Tags: News and Views Source Type: research

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