The Nrf2/HO-1 Pathway Mediates the Antagonist Effect of L-Arginine On Renal Ischemia/Reperfusion Injury in Rats

Conclusion: These findings suggested that L-arginine/NO reduces renal dysfunction associated with I/R of the kidney and may act as a trigger to regulate the NF- κB, HSP70 and Nrf2/HO-1 signaling cascades.Kidney Blood Press Res 2017;42:519 –529
Source: Kidney and Blood Pressure Research - Category: Urology & Nephrology Source Type: research