Sildenafil should be avoided in valve disease with residual pulmonary hypertension

(European Society of Cardiology) Sildenafil should not be used to treat residual hypertension in patients with valvular heart disease, according to late-breaking results from the SIOVAC trial presented today in a Hot Line LBCT Session at ESC Congress. The off-label use of the drug led to worse clinical outcomes including a doubled risk of hospitalization compared to placebo.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news