Activation of PKC triggers rescue of NPC1 patient specific iPSC derived glial cells from gliosis
Niemann-Pick disease Type C1 (NPC1) is a rare progressive neurodegenerative disorder caused by mutations in the NPC1 gene. The pathological mechanisms, underlying NPC1 are not yet completely understood. Especiall...
Source: Orphanet Journal of Rare Diseases - Category: Internal Medicine Authors: Franziska Peter, Sebastian Rost, Arndt Rolfs and Moritz J. Frech Tags: Research Source Type: research