Metastatic Synovial Sarcoma of Lung Mimicking PE and DVT Metastatic Synovial Sarcoma of Lung Mimicking PE and DVT
What can we learn from this case of metastatic synovial sarcoma initially misdiagnosed as deep venous thrombosis?Thorax
Publication date: Available online 10 October 2020Source: Journal of Vascular Surgery: Venous and Lymphatic DisordersAuthor(s): N.G. Shah, B.C. Wible, J.A. Paulisi, M. Zaki, P. Lamparello, A. Sista, M. Sadek, G.R. Jacobowitz, T.S. Maldonado
CONCLUSIONS: As the present study was the first investigation on the coagulation status in patients with AA, elevated D-dimer levels in alopecia areata may suggest a deficient coagulation in these patients that may contribute to an increase in the risk of thrombosis. Further studies are needed to evaluate this hypothesis using a larger sample size. PMID: 33034439 [PubMed - as supplied by publisher]
New J. Chem., 2020, Advance Article DOI: 10.1039/D0NJ02249G, PaperChuan-ce Sun, Li-chuan Zhang, Cheng-long Gao, Hao-ran Zhang, Ri-lei Yu, Cong-min Kang Serum and glucocorticoid-regulated protein kinase 1 that can promote the growth of tumor cells is highly expressed in many tumors. Sarcoma gene plays an important role in the pathogenesis of cancer and is an important kinase in tumor cell expression pathways. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Publication date: Available online 7 October 2020Source: European UrologyAuthor(s): Amit Bansal, Anant Kumar
Synovial sarcomas are a rare subtype of soft tissue sarcomas mostly located in the lower extremities. The authors report a case of synovial sarcoma in a 15-year-old adolescent girl with several unusual features including age, intrapelvic retroperitoneal location of the primary tumor, and presentation with right abdominal tenderness and compression of the iliac vessels with thrombosis of the right iliac and femoral vein.
Conclusions: The primary renal synovial sarcoma often represented a cystic-solid mass with inhomogeneous density and inhomogeneous enhancement of the solid components, but the smaller mass could be expressed as a homogeneous density in the CT examination. 18F-FDG PET/CT represented different levels of mass metabolism, and its degree of metabolism may be related to the proliferative activity of tumor cells and the degree of malignancy.
emann C Abstract Aminopeptidase N (CD13) is expressed on tumor vasculature and tumor cells. It represents a candidate for targeted therapy, e.g., by truncated tissue factor (tTF)-NGR, binding to CD13, and causing tumor vascular thrombosis. We analyzed CD13 expression by immunohistochemistry in 97 patients with STS who were treated by wide resection and uniform chemo-radio-chemotherapy. Using a semiquantitative score with four intensity levels, CD13 was expressed by tumor vasculature, or tumor cells, or both (composite value, intensity scores 1-3) in 93.9% of the STS. In 49.5% tumor cells, in 48.5% vascular/perivas...
We report a unique case of a 21-year-old young male with the diagnosis of a biphasic renal SS with extensive venous system thrombosis involving the inferior vena cava, bilateral iliac, and femoral vessels which was managed by radical nephrectomy and tumor thrombectomy followed by adjuvant chemotherapy.
Introduction Synovial sarcoma (SS) is a highly aggressive mesenchymal malignancy that usually originates from deep soft tissues of the extremities. Lungs are the most common metastatic site, but rare cases of vascular metastasis have been reported. Here we report a case of metastatic SS in a 26-year-old male patient with right lower extremity oedema first misdiagnosed as deep venous thrombosis (DVT). CT pulmonary angiogram (CTPA) revealed a mass lesion inside the right pulmonary artery mimicking PE. The diagnosis of SS was established by histopathological examination acquired by endobronchial ultrasound-guided transbronchi...
Abstract Synovial sarcomas occurs primarily in the soft tissues, mostly in para-articular regions of the extremities. These tumors have been described in other unusual locations like the pleura, lungs, mediastinum, and kidneys. Primary synovial sarcoma of the kidney is a recently described entity; to date, a total of approximately 35 cases have been reported. Only three cases of primary synovial sarcoma of kidney with IVC thrombus have been reported so far. Here we present the case of a 44 year old gentleman, with primary synovial sarcoma of the left kidney with caval thrombus.