Persistent detection of dengue virus RNA in vaginal secretion of a woman returning from Sri Lanka to Italy, April 2017

We describe the dynamics of dengue virus (DENV) infection in a woman in her mid-30s who developed fever after returning from Sri Lanka to Italy in April 2017. Laboratory testing demonstrated detectable DENV-RNA in plasma, urine, saliva, vaginal secretion. Persistent shedding of DENV-RNA was demonstrated in vaginal secretion, and DENV-RNA was detectable in the pelleted fraction up to 18 days from symptom onset. These findings give new insights into DENV vaginal shedding and vertical transmission.
Source: Eurosurveillance - Category: Infectious Diseases Source Type: research

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[Trastornos gastrointestinales funcionales después de un episodio de dengue no grave sin signos de alarma]. Biomedica. 2019 Aug 01;39(Supl. 2):93-100 Authors: Velasco-Benítez CA, Ortiz-Rivera CJ Abstract Introducción. La patogenia de los trastornos funcionales gastrointestinales involucra agentes infecciosos como los virus. Objetivo. Investigar el desarrollo de trastornos funcionales gastrointestinales en niños, a los 3, 6, 9 y 12 meses después de un episodio de dengue no grave sin signos de alarma. Materiales y métodos. Se hizo un estudio de cohorte de 73 ni&n...
Source: Biomedica : Revista del Instituto Nacional de Salud - Category: International Medicine & Public Health Tags: Biomedica Source Type: research
Honduras is battling an especially deadly outbreak of dengue fever, with at least 135 people dead from dengue there this year, nearly two-thirds of them children
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
lmair Flaviviruses are the most medically relevant group of arboviruses causing a wide range of diseases in humans and are associated with high mortality and morbidity, as such posing a major health concern. Viruses belonging to this family can be endemic (e.g., dengue virus), but can also cause fulminant outbreaks (e.g., West Nile virus, Japanese encephalitis virus and Zika virus). Intense research efforts in the past decades uncovered shared fundamental strategies used by flaviviruses to successfully replicate in their respective hosts. However, the distinct features contributing to the specific host and tissue tropi...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
Dengue is a mosquito-borne viral infection that has become a major public health concern worldwide. Presently, there is no specific vaccine or treatment available for dengue viral infection.
Source: BMC Complementary and Alternative Medicine - Category: Complementary Medicine Authors: Tags: Research article Source Type: research
Viral Immunology, Ahead of Print.
Source: Viral Immunology - Category: Allergy & Immunology Authors: Source Type: research
by Sarah Anne J. Guagliardo, Yoosook Lee, Amanda A. Pierce, Jacklyn Wong, Yui Yin Chu, Amy C. Morrison, Helvio Astete, Berry Brosi, Gonzalo Vazquez-Prokopec, Thomas W. Scott, Uriel Kitron, Steven T. Stoddard In the Americas, as in much of the rest of the world, the dengue virus vectorAedes aegypti is found in close association with human habitations, often leading to high population densities of mosquitoes in urban settings. In the Peruvian Amazon, this vector has been expanding to rural communities over the last 10 –15 years, but to date, the population genetic structure ofAe.aegypti in this region has not been cha...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
Dengue is one of the most prevalent infectious tropical diseases in the world, with high incidence in over 100 countries. Rapid and reliable diagnosis of dengue is of great importance for public health. To simplify molecular diagnostics, isothermal amplification techniques have recently emerged as an alternative to conventional methods of deoxyribonucleic acid (DNA) amplification. Here, we developed a one-step method for dengue virus detection from real sample based on RT-LAMP (reverse transcription-loop mediated isothermal amplification) in a disposable microdevice. The reaction was thermally controlled with a thermoblock...
Source: Journal of the Brazilian Chemical Society - Category: Chemistry Source Type: research
We describe here network buildin g methods that can maximize edges between nodes of different data types leading to integrated networks, networks that have a large number of edges that link nodes of different–omic types (transcripts, proteins, lipids etc). We systematically rank several network inference methods and demonstrate t hat, in many cases, using a random forest method, GENIE3, produces the most integrated networks. This increase in integration does not come at the cost of accuracy as GENIE3 produces networks of approximately the same quality as the other network inference methods tested here. Using GENIE3, ...
Source: PLoS Computational Biology - Category: Biology Authors: Source Type: research
ver The unprecedented outbreak of Zika virus (ZIKV) infection in the Americas from 2015 to 2017 prompted the publication of a large body of vector competence data in a relatively short period of time. Although differences in vector competence as a result of disparities in mosquito populations and viral strains are to be expected, the limited competence of many populations of the urban mosquito vector, Aedes aegypti, from the Americas (when its susceptibility is viewed relative to other circulating/reemerging mosquito-borne viruses such as dengue (DENV), yellow fever (YFV), and chikungunya viruses (CHIKV)) has proven a ...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
[New Times] Members of the East African Legislative Assembly (EALA) who held a meeting in Kigali on Friday to discuss regional countries' preparedness for Ebola and Dengue fever are concerned that there is no common regional policy, practice or guidelines on responding to an outbreak of epidemic diseases.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
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