16 Dead as Strong Typhoon Floods Macau, Southern China

HONG KONG (AP) — The most powerful typhoon to hit the southern Chinese region in more than half a century left at least 16 dead as a sudden deluge swamped the gambling hub of Macau, submerging streets and stranding residents. Macau said Thursday that eight people were killed in the former Portuguese colony, including two men found overnight in a submerged parking garage. Another 153 were injured amid extensive flooding, power outages, and the smashing of doors and windows by high winds and driving rain. "It's a calamity, the losses are high and a lot of buildings need repair," said Macau lawmaker Jose Pereira Coutinho, adding that he heard from many people who still had no water or electricity a day after Typhoon Hato tore across the 30-square kilometer (19-square mile) territory. Coutinho said the flooding was at its worst in the older parts of the city's downtown, where narrow lanes date back from Macau's time as a Portuguese colony for more than four centuries. "People were just swimming, they cried for help. There were no boats. The water came so suddenly," said Coutinho, who slammed the city government for having "reacted so slowly and so badly." Casinos downtown "were either closed or barely operating," while some resorts in the newer Cotai district were in better shape but operating without air conditioning, Union Gaming Research analyst Grant Govertsen said in a report. The chief executive of Macau's local gove...
Source: JEMS: Journal of Emergency Medical Services News - Category: Emergency Medicine Authors: Tags: Major Incidents News Source Type: news

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In this study, we examined the dynamics of phenotypic and transcriptional profiles inSaccharomyces cerevisiae following semi-lethal X-ray irradiation. Post-irradiation, reproductive death was revealed as the predominant form of death inS. cerevisiae and almost all the irradiated cells were physically present and intact. In addition, cell cycle arrest reached its peak and cell division was at its valley at 2  h. Cell cycle arrest, cell division potential, DNA damage, and mitochondrial transmembrane potential (MTP) showed significant recovery at 4 h (P >  0.05 vs. control). The improvements of DNA ...
Source: World Journal of Microbiology and Biotechnology - Category: Microbiology Source Type: research
AbstractOral and maxillofacial surgeons are often called in emergency situations during odd hours to manage facial trauma cases. While addressing these patients, many a times the surgeon might require to keep the patients mouth open for long time while accessing intraoral injuries. This can become difficult for a surgeon if in case regular dental mouth props/mouth gags are not available at a particular surgical setup. The author here describes a technique of using a standard disposable syringe as a mouth prop in emergency cases to access and repair any intraoral injury in absentia of a regular mouth prop/mouth gag.
Source: Journal of Maxillofacial and Oral Surgery - Category: ENT & OMF Source Type: research
Publication date: Available online 8 December 2018Source: The American Journal of SurgeryAuthor(s): Tamar B. Nobel, Shruti Zaveri, Prerna Khetan, Celia M. DivinoABSTRACTBackgroundRecent data has demonstrated that postoperative patients are at risk of chronic opioid abuse. It is unknown whether surgeon postoperative opioid prescribing changed as the opioid crisis entered its peak.MethodsThe Institutional Data Warehouse was queried to identify patients who underwent three common elective ambulatory procedures between 2014-2018 (n=3495), including: laparoscopic cholecystectomy, laparoscopic inguinal hernia repair (IHR), and o...
Source: The American Journal of Surgery - Category: Surgery Source Type: research
In conclusion, this is the first report to show that pyroptotic cell death occurs in the aging brain and that the inflammasome can be a viable target to decrease the oxidative stress that occurs as a result of aging. Reducing Levels of Protein Manufacture Slows Measures of Aging in Nematodes https://www.fightaging.org/archives/2018/12/reducing-levels-of-protein-manufacture-slows-measures-of-aging-in-nematodes/ Researchers here demonstrate that an antibiotic slows aging in nematode worms, providing evidence for it to work through a reduction in protein synthesis. Beyond a slowing of aging, one of the con...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Publication date: Available online 7 December 2018Source: Environmental Toxicology and PharmacologyAuthor(s): Ayse Basak Engin, Atilla EnginAbstractAlthough most countries regulate the aflatoxin levels in food by legislations, high amounts of aflatoxin B1 (AFB1)-DNA adducts can still be detected in normal and tumorous tissue obtained from cancer patients. AFB1 cannot directly interact with DNA unless it is biotransformed to AFB1-8, 9-epoxide via cytochrome p450 enzymes. This metabolite spontaneously and irreversibly attaches to guanine residues to generate highly mutagenic DNA adducts. AFB1-induced mutation of ATM kinase r...
Source: Environmental Toxicology and Pharmacology - Category: Environmental Health Source Type: research
ConclusionsIf possible, elective ventral repair should be postponed until after last pregnancy. A non-mesh repair seems appropriate for smaller primary ventral hernia in women who plan future pregnancies. Umbilical hernia during pregnancy seems very rare and seldom requires repair pre- and post-partum. Routine practice of umbilical hernia repair in combination with cesarean section cannot be recommended. PROSPERO: CRD42017073736.
Source: The American Journal of Surgery - Category: Surgery Source Type: research
This study aims to analyze early outcomes of one humanitarian surgical organization to show that safe essential general surgery can be provided in the context of STSMs.Records from 6 STSMs to Sierra Leone and Ghana were reviewed for early complications and analysis performed to identify associated factors. Missions performed elective, general surgery on low risk patients, with adherence to patient safety protocols.No perioperative mortality occurred from 372 procedures, most frequently inguinal hernia repair (54%). Seventeen surgical (5%), 3 infectious (1.2%), and 6 anesthesia (2%) complications were reported. Only younger...
Source: The American Journal of Surgery - Category: Surgery Source Type: research
Conclusion: This study shows that SIM negatively affects the inflammatory and repair phases of the postinjury muscle regeneration. These findings are unique, strengthen the available knowledge on the side effects of SIM, and provide evidence showing that statin therapy is associated with an increased risk of impairment of the regenerative capacity of muscle. PMID: 30519583 [PubMed - in process]
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Publication date: February 2019Source: Biomedicine &Pharmacotherapy, Volume 110Author(s): Irina G. Danilova, Boris G. Yushkov, Irina A. Kazakova, Anna V. Belousova, Artem S. Minin, Musa T. AbidovAbstractPharmacological interventions which could be hepatoprotective, depending on bioavailability, anti-inflammatory and macrophage-targeting potential of drugs, are still at early preclinical stages. Existing evidence from many animal models of liver injury, as well as from human data, indicate that pharmacological and/or phytochemical interventions have limited impact on liver recovery. Recent studies on stem cell therapies...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
CONCLUSION: The high prevalence of chronic post-hernioplasty pain raises the urgent need for raising awareness regarding this issue among health care professionals. The main areas for improvement are diagnosis, follow-up and treatment of pain. PMID: 30521455 [PubMed - in process]
Source: Acta Medica Portuguesa - Category: General Medicine Tags: Acta Med Port Source Type: research
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