New use of blood cleaning device saves high-risk patients with liver failure

(University of Maryland Medical Center) University of Maryland School of Medicine researchers report that a device that removes toxins from the blood can also effectively provide a bridge to liver transplantation or buy time for a traumatically injured liver to heal, suggesting broader uses for the device than previously thought.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news

Related Links:

We presently forget 98% of everything we experience. That will go away in favor of perfect, controllable, configurable memory. Skills and knowledge will become commodities that can be purchased and installed. We will be able to feel exactly as we wish to feel at any given time. How we perceive the world will be mutable and subject to choice. How we think, the very fundamental basis of the mind, will also be mutable and subject to choice. We will merge with our machines, as Kurzweil puts it. The boundary between mind and computing device, between the individual and his or her tools, will blur. Over the course of the ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Authors: Coles N, Comeau I, Munoz T, Harrington J, Mendoza-Londono R, Schulze A, Kives S, Kamath BM, Hamilton J Abstract McCune-Albright syndrome (MAS) is a rare genetic disorder characterized by café-au-lait macules, polyostotic fibrous dysplasia and multiple endocrinopathies. Liver involvement, although described, is a rare complication. We review the case of a child with MAS whose initial presentation was characterized by severe neonatal cholestasis. The case demonstrates a severe phenotype of persistent cholestasis in MAS requiring liver transplantation, which has been previously considered to be a more ...
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - Category: Endocrinology Tags: J Clin Res Pediatr Endocrinol Source Type: research
Abstract Aims: Hepatorenal syndrome (HRS) decreases survival of cirrhotic patients. The outcomes of HRS after liver transplantation (LT) were inconsistently reported. We conducted a systematic review and meta-analysis study to estimate the post-LT rates of death and HRS reversal. Methods: A thorough search of literatures was performed on PubMed, Scopus, and conference abstracts for reports on post-LT survival and HRS reversal. Data for the posttransplant rates of HRS reversal, death, and acute rejection were extracted. The rates were pooled using inverse variance method if there was no heterogeneity between s...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Purpose of review Unlike in orthotopic heart transplant (OHT) setting where toxoplasma prophylaxis is a standard practice in pretransplant toxoplasma seronegative recipients who have received donor hearts from seropositive donors (D+/R-), there is no consensus regarding prophylaxis in non-OHT recipients. Recent findings The incidence of toxoplasma disease in non-OHT recipients is less than 1% but its true burden is underestimated. Among 31 cases of toxoplasma disease reported from 2004 through 2017, renal and liver transplant recipients comprised of 90% of cases. A total of 94% of 18 recipients with known pretransplan...
Source: Current Opinion in Organ Transplantation - Category: Surgery Tags: INFECTIOUS COMPLICATIONS IN TRANSPLANTATION: Edited by Shimon Kusne Source Type: research
Pediatric Transplantation, EarlyView.
Source: Pediatric Transplantation - Category: Transplant Surgery Authors: Source Type: research
CONCLUSIONS This study demonstrates the feasibility of HMGB-1 detection in the graft effluent after cold storage. Along with conventional prognostic scores, it may be helpful to predict the early fate of a graft in human liver transplantation. PMID: 30002362 [PubMed - in process]
Source: Annals of Transplantation - Category: Transplant Surgery Authors: Tags: Ann Transplant Source Type: research
Authors: Elalfy H, Besheer T, El-Maksoud MA, Farid K, Elegezy M, El Nakib AM, El Aziz MA, El-Khalek AA, El-Morsy A, Elmokadem A, Elsamanoudy AZ, El-Bendary MA Abstract BACKGROUND: The first-line treatment option for intermediate-stage hepatocellular carcinoma is transarterial chemoembolization. Certain blood indices, such as lymphocyte/monocyte ratio (LMR), lymphocyte count, neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), monocyte-granulocyte/lymphocyte ratio (MGLR) and red blood cell distribution width (RDW) are prognostic biomarkers in certain diseases. The model for end-stage liver disease (M...
Source: British Journal of Biomedical Science - Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research
Conditions:   Liver Diseases;   End Stage Liver Disease;   Frailty Interventions:   Device: Nokia GO Wearable StepTracker;   Other: Medication Reminder;   Other: Weekly Check-in appointment with study team or provider Sponsor:   University of Pennsylvania Recruiting
Source: - Category: Research Source Type: clinical trials
Publication date: Available online 12 July 2018Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Norma Arteiro Filgueira, Camilla Maria de Alencar Saraiva, Norma Thomé Jucá, Matheus Filgueira Bezerra, Claudio Moura LacerdaAbstractSchistosomiasis affects approximately 207 million people in 76 countries. The association between hepatocellular carcinoma (HCC) and Schistosoma mansoni infection (SMI) has been investigated. Studies using animal models suggest that the parasite may accelerate the oncogenic process when combined with other factors, such as hepatitis C virus infection or exposure to a car...
Source: The Brazilian Journal of Infectious Diseases - Category: Infectious Diseases Source Type: research
ConclusionMR cholangiopancreatography and MR imaging at 3 T device are extremely reliable for detecting biliary complications after liver transplantation.
Source: European Journal of Radiology - Category: Radiology Source Type: research
More News: International Medicine & Public Health | Liver | Liver Transplant | Science | Transplants | University of Maryland | Urology & Nephrology