Many heart failure patients don ’t recognize the risks of their illness

(Reuters Health) - Even though doctors think most people with heart failure have a high likelihood of requiring a heart transplant or dying from complications of their illness, a small U.S. study suggests that many patients see a much rosier picture of their future.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

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Treatment of advanced heart failure with implantable LVADs is increasing, driven by profound unmet patient need despite potential serious complications: bleeding, infection, and thrombus. The experimental objective was to develop a sensitive imaging approach to assess early thrombus accumulation in LVADs under operational high flow and high shear rates.Methods: A monomeric bifunctional ligand with a fibrin-specific peptide, a short spacer, and 99mTc chelating amino acid sequence (F1A) was developed and compared to its tetrameric PEG analogue (F4A).Results: 99mTc attenuation by LVAD titanium (1 mm) was 23%. 99mTc-F1A affini...
Source: Theranostics - Category: Molecular Biology Authors: Tags: Research Paper Source Type: research
Publication date: Available online 19 June 2018 Source:PM&R Author(s): Sarah M. Eickmeyer, Kim D. Barker, Anjum Sayyad, Leslie Rydberg As an increasing number of patients with advanced heart failure are receiving a Left Ventricular Assist Device (LVAD) as either destination therapy or bridge to transplantation, there is increasing attention on functional outcomes and quality of life after LVAD implantation. Rehabilitation providers in the acute inpatient rehabilitation setting increasingly will treat patients with LVAD and should understand the exercise physiology, medical management, rehabilitation considerations, an...
Source: PMandR - Category: Rehabilitation Source Type: research
Abstract Ensuring patient safety is a priority of medical care because iatrogenic injury has been a primary concern. Medications are an important source of medical errors, and kidney disease is a thoroughfare of factors threatening safe administration of medicines. Principal among these is reduced kidney function because almost half of all medications used are eliminated via the kidney. Additionally, kidney patients often suffer from multimorbidity, including diabetes, hypertension, and heart failure, with a range of prescribers who often do not coordinate treatments. Patients with kidney disease are also suscepti...
Source: Clinical Journal of the American Society of Nephrology : CJASN - Category: Urology & Nephrology Authors: Tags: Clin J Am Soc Nephrol Source Type: research
Authors: Spiliopoulos S, Hergesell V, Wasler A, Dapunt O Abstract Due to the declining instances of organ donation, total artificial heart (TAH) therapy is of increasing importance for the management of end-stage biventricular heart failure. We introduce the currently most important established and novel TAH systems (SynCardia, CARMAT, ReinHeart, BiVACOR), report clinical outcomes and discuss technical requirements for the successful implementation of TAH therapy as an alternative to cardiac transplantation. PMID: 29902152 [PubMed - as supplied by publisher]
Source: Biomedizinische Technik/Biomedical Engineering - Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research
Baylor St. Luke ’s Medical Center announced June 15 that it has reactivated its heart-transplant surgery program and is accepting donor hearts for transplants again. The hospital voluntarily suspended the surgery program on June 1. The two-week suspension did not affect other heart-failure procedures, such as he art-pump implants, or any other transplant programs across the hospital.  According to a message posted on the hospital’s website, the following steps have been taken since June 1: A…
Source: Health Care:Physician Practices headlines - Category: American Health Authors: Source Type: news
Introduction The prognostic value of peak V˙O2 and V˙E/V˙CO2 slope measured during cardiopulmonary exercise (CPX) testing has been well established in patients with advanced heart failure, but blood pressure response to exercise is less well characterized. Methods We retrospectively studied 151 outpatients who underwent CPX testing as part of an advanced heart failure evaluation. The outcome of interest was failure of medical management, defined by death, cardiac transplantation, or left ventricular assist device placement. Patients were stratified into tertiles by change in systolic blood pressure (SBP) (
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: Clinical Sciences Source Type: research
CONCLUSION: Baseline big ET-1 > 0.56 pmol/L was independently associated with higher all-cause mortality and HFH among CRT recipients, and therefore can be added to the marker panel used for stratifying high risk CRT patients for priority treatment. PMID: 29913121 [PubMed - as supplied by publisher]
Source: Clinical Biochemistry - Category: Biochemistry Authors: Tags: Clin Biochem Source Type: research
Pulsatility seems to have a teleological role because evolutionary hierarchy favors higher ordered animals with more complex, multichamber circulatory systems that generate higher pulse pressure compared with lower ordered animals. Yet despite years of such natural selection, the modern generation of continuous-flow left ventricular assist devices (CF-LVADs) that have been increasingly used for the last decade have created a unique physiology characterized by a nonpulsatile, nonlaminar blood flow profile with the absence of the usual large elastic artery Windkessel effect during diastole. Although outcomes and durability h...
Source: Circulation: Heart Failure - Category: Cardiology Authors: Tags: Translational Studies, Vascular Biology, Heart Failure, Cardiovascular Surgery, Transplantation Advances in Mechanical Circulatory Support Source Type: research
The allocation of donor hearts evolves in response to the changing landscape of advanced heart failure therapies and expanded understanding of donor/recipient matching. The novel, heart allocation algorithm is a natural response to the success of mechanical circulatory support (MCS) and further aligns severity of illness with urgency. In the novel, 6-status system, candidates supported with veno-arterial, extracorporeal membrane oxygenation devices (ECMO) and biventricular, extracorporeal ventricular assist devices (VAD) receive Status 1 urgency, while Status 2 urgency comprises candidates with univentricular extracorporea...
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Editorial Source Type: research
Conclusion18F-FDG PET/CT and radiolabeled leucocyte scintigraphy single-photon emission computed tomography carry high performance in the diagnostic of LVAD infections.18F-FDG PET/CT shows significantly higher sensitivity and could be proposed as first-line nuclear medicine procedure.
Source: Journal of Nuclear Cardiology - Category: Nuclear Medicine Source Type: research
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