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Is It All About Age or Personalized Haplo HCT for Elderly?

The number of allogeneic transplants performed each year with curative intent for older adults with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) continued to rise during the past decade. Much of the progress in the use of alloHCT in older adults is due to reduced-intensity conditioning (RIC) regimens, which have allowed many older patients with AML or MDS to receive curative allogeneic hematopoietic cell transplantation (alloHCT).1 Without RIC, these older patients would otherwise be unfit for alloHCT because of the toxicities of myeloablative conditioning.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Source Type: research

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