Glucagon-like peptide-1 receptor agonist stimulates mitochondrial bioenergetics in human adipocytes.

In conclusion, exendin-4 activates the sirtuin pathway and increases energy expenditure in human adipocytes. Our results suggest another mechanism that may be responsible for body weight reduction observed in patients using GLP-1RAs. PMID: 28822994 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/28822994?dopt=Abstract

Source: Acta Biochim Pol - August 19, 2017 Category: Biochemistry Authors: Góralska J, Śliwa A, Gruca A, Raźny U, Chojnacka M, Polus A, Solnica B, Malczewska-Malec M Tags: Acta Biochim Pol Source Type: research