Saffron (Crocus sativus) intake provides nutritional preconditioning against myocardial ischemia-reperfusion injury in Wild Type and ApoE(-/-) mice: involvement of Nrf2 activation
Saffron is an antioxidant herbal derivative; however, its efficacy as a nutritional cardioprotective agent has not been fully elucidated. We investigated the cardioprotective properties of a standardized saffron aqueous extract (SFE) against ischemia/reperfusion (I/R) injury in Wild-Type (WT) and ApoE(-/-) mice and the underlying molecular mechanisms.
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - Category: Nutrition Authors: P. Efentakis, A. Rizakou, E. Christodoulou, A. Chatzianastasiou, M.G. L ópez, R. León, E. Balafas, N.P.E. Kadoglou, I. Tseti, H. Skaltsa, N. Kostomitsopoulos, E.K. Iliodromitis, G. Valsami, I. Andreadou Source Type: research
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