Extracellular HSP70 Activates ERK1/2, NF-kB and Pro-Inflammatory Gene Transcription Through Binding with RAGE in A549 Human Lung Cancer Cells

Conclusions: Our results evidence eHSP70 as a novel RAGE agonist capable of influence the cross-talk between cancer and immune system cells.Cell Physiol Biochem 2017;42:2507 –2522
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research