Influence of Tetrabromobisphenol A, with or without Concurrent Triclosan, upon Bisphenol A and Estradiol Concentrations in Mice

Conclusion: These data indicate that TBBPA, triclosan, and BPA interact in vivo, consistent with evidence that TBBPA and triclosan inhibit enzymes that are critical for BPA and E2 metabolism. https://doi.org/10.1289/EHP1329 Received: 04 November 2016 Revised: 11 April 2017 Accepted: 13 April 2017 Published: 21 August 2017 Address correspondence to D. deCatanzaro, Dept. of Psychology, Neuroscience &Behaviour, McMaster University, 1280 Main St. West, Hamilton ON L8S 4K1, Canada. Telephone: (905) 525-9140, ext. 23014. Email: decatanz@mcmaster.ca Supplemental Material is available online (https://doi.org/10.1289/EHP1329). The authors declare they have no actual or potential competing financial interests. Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days. Supplemental Material PDF (215 KB) Note to readers with disabilities: EHP has provided a 508-conformant table of contents summarizing the Supplemental Material for this article (see below) so readers with disabilities may determine whether they wish to access the ...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research

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CONCLUSIONS: This study provides evidence of a dynamic process of white matter change occurring beyond the initial phases of recovery after moderate to severe TBI. The observed relationship between structural reorganization and changes in cognitive performance has implications for rehabilitation potential in more chronic phases of recovery. PMID: 31017479 [PubMed - as supplied by publisher]
Source: Brain Injury - Category: Neurology Tags: Brain Inj Source Type: research
In the fields of tissue engineering, drug delivery, and filtering material, electrospun ultrafine fibers with micropores have important applications. A scanning electron microscope (SEM) is typically used to observe the microstructure of ultrafine fibers, but SEM has disadvantages, such as small ...
Source: Applied Optics - Category: Physics Authors: Source Type: research
This study examined how two aesthetic features of infographics affect people's evaluation of information presented in infographic: colour and visual complexity. The findings suggested colour and visual complexity were both strong predictors of information evaluation in infographic and they should be chosen carefully in the design of infographics. PMID: 31014148 [PubMed - as supplied by publisher]
Source: Journal of Visual Communication in Medicine - Category: Information Technology Tags: J Vis Commun Med Source Type: research
Authors: Kim TJ, Song J, Kim YS, Huh J, Kang IS, Yang JH, Jun TG Abstract OBJECTIVES: We aimed to investigate the outcome of tricuspid valve repair (TVR) performed concomitantly with pulmonary valve replacement in repaired tetralogy of Fallot (TOF) patients. DESIGN: This retrospective study included all patients who underwent pulmonary vale replacement from 2000 to 2016 after TOF correction. TVR patient data were compared to those of patients who underwent pulmonary vale replacement alone. RESULTS: Thirty-eight patients were enrolled. The degree of tricuspid regurgitation was significantly decreased after o...
Source: Scandinavian Cardiovascular Journal - Category: Cardiology Tags: Scand Cardiovasc J Source Type: research
In conclusion, it was identified that silencing of miR‑193a‑3p through hypermethylation can promote HER2 positive breast cancer progress by targeting GRB7, ERK1/2 and FOXM1 signaling. The function of miR‑193a‑3p in HER2 positive breast cancer implicates its potential application in therapy. PMID: 31017268 [PubMed - in process]
Source: International Journal of Molecular Medicine - Category: Molecular Biology Authors: Tags: Int J Mol Med Source Type: research
MicroRNA‑576‑3p inhibits the migration and proangiogenic abilities of hypoxia‑treated glioma cells through hypoxia‑inducible factor‑1α. Int J Mol Med. 2019 Jun;43(6):2387-2397 Authors: Hu Q, Liu F, Yan T, Wu M, Ye M, Shi G, Lv S, Zhu X Abstract The most common and aggressive type of brain cancer in adults is glioblastoma multiforme (GBM), and hypoxia is a common feature of glioblastoma. As the histological features of glioma include capillary endothelial cell proliferation, they are highly prone to invading the surrounding normal brain tissue, which is often one of the reasons for the ...
Source: International Journal of Molecular Medicine - Category: Molecular Biology Authors: Tags: Int J Mol Med Source Type: research
Detection of N6‑methyladenosine modification residues (Review). Int J Mol Med. 2019 Jun;43(6):2267-2278 Authors: Zhu W, Wang JZ, Xu Z, Cao M, Hu Q, Pan C, Guo M, Wei JF, Yang H Abstract Among a number of mRNA modifications, N6‑methyladenosine (m6A) modification is the most common type in eukaryotes and nuclear‑replicating viruses. m6A has a significant role in numerous cancer types, including leukemia, brain tumors, liver cancer, breast cancer and lung cancer. Although m6A methyltransferases are essential during RNA modifications, the biological functions of m6A and the underlying mechanisms rem...
Source: International Journal of Molecular Medicine - Category: Molecular Biology Authors: Tags: Int J Mol Med Source Type: research
In conclusion, IL‑18 served a dual function in colitis by regulating the function of goblet cells. The anti‑inflammatory effects of IL‑18 were observed in the early stage of colitis‑induced inflammation, while the pro‑inflammatory effects were observed in the later stages of the disease. PMID: 31017261 [PubMed - in process]
Source: International Journal of Molecular Medicine - Category: Molecular Biology Authors: Tags: Int J Mol Med Source Type: research
Analysis of a nanoparticle‑enriched fraction of plasma reveals miRNA candidates for Down syndrome pathogenesis. Int J Mol Med. 2019 Jun;43(6):2303-2318 Authors: Salvi A, Vezzoli M, Busatto S, Paolini L, Faranda T, Abeni E, Caracausi M, Antonaros F, Piovesan A, Locatelli C, Cocchi G, Alvisi G, De Petro G, Ricotta D, Bergese P, Radeghieri A Abstract Down syndrome (DS) is caused by the presence of part or all of a third copy of chromosome 21. DS is associated with several phenotypes, including intellectual disability, congenital heart disease, childhood leukemia and immune defects. Specific microR...
Source: International Journal of Molecular Medicine - Category: Molecular Biology Authors: Tags: Int J Mol Med Source Type: research
Abstract Mitochondria are crucial for neuronal cell survival and death through their functions in ATP production and the intrinsic pathway of apoptosis. Mitochondrial dysfunction is considered to play a central role in several serious human diseases, including neurodegenerative diseases, such as Parkinson's and Alzheimer's disease and ischemic neurodegeneration. The aim of the present study was to investigate the impact of transient global brain ischemia on the expression of selected proteins involved in mitochondrial dynamics and mitochondria‑associated membranes. The main foci of interest were the proteins mit...
Source: International Journal of Molecular Medicine - Category: Molecular Biology Authors: Tags: Int J Mol Med Source Type: research
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