Chelerythrine Attenuates Renal Ischemia/ Reperfusion-induced Myocardial Injury by Activating CSE/H2S via PKC/NF- κB Pathway in Diabetic Rats

Conclusion: These findings suggest that CHE-pretreatment may exert a protective effect on the myocardium against RI/RMI by activating endogenous CSE/H2S via PKC/NF- κB pathway in STZ-induced diabetic rats. Further studies are needed defining underlying mechanisms.Kidney Blood Press Res 2017;42:379 –388
Source: Kidney and Blood Pressure Research - Category: Urology & Nephrology Source Type: research