Severe disruption and disorganization of dermal collagen fibrils in early striae gravidarum.

CONCLUSIONS: Early SG display marked separation of collagen bundles and emergence of disorganized collagen fibrils that fail to form bundles. These alterations may reflect ineffective repair of collagen bundles disrupted by intense skin stretching. Persistent disruption of the collagenous extracellular matrix likely promotes formation and atrophy of SG. This article is protected by copyright. All rights reserved. PMID: 28815554 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/28815554?dopt=Abstract

Source: The British Journal of Dermatology - August 17, 2017 Category: Dermatology Authors: Wang F, Calderone K, Do TT, Smith NR, Helfrich YR, Johnson TRB, Kang S, Voorhees JJ, Fisher GJ Tags: Br J Dermatol Source Type: research