Effect of AP102, a subtype 2 and 5 specific somatostatin analog, on glucose metabolism in rats

ConclusionsAP102 is a new dual SSTR2/SSTR5-specific somatostatin analog that acutely reduces growth hormone but does not cause hyperglycemia during acute or chronic administration in a healthy rat model. Further studies in diabetic animals and in humans are necessary to determine the potential utility of AP102 in the clinical setting.
Source: Endocrine - Category: Endocrinology Source Type: research