Pediatric Admissions After Dental Care Under General Anesthesia: A Retrospective Study at a Tertiary Care Center
Thank you, Drs Fisher, Benson, and Imray, for your interest in our article and for highlighting some of the evidence to support the use of general anesthesia for its neuroprotective effects, which are derived from the uncoupling of cerebral metabolism and blood flow. Although general anesthesia likely provides some neuroprotective effect (so-called luxury perfusion), we found that it does not significantly lower the rate of clinically significant strokes in our study, as evidenced by the equivalent rate of stroke between patients who had local anesthesia and those who were routinely shunted under general anesthesia.
The Substantia Nigra pars reticulata (SNr) is a promising target for deep brain stimulation (DBS) to treat the gait and postural disturbances in Parkinson ’s Disease (PD). The effects of DBS in subregions of the SNr on the treatment of gait and postural disturbances in PD is not clear. We recorded neural activity in subregions of SNr using tungsten microwire electrodes in anesthetized rats and hypothesized that changes in coherence spectra between n eighboring microelectrode recordings correlated with electrode position within subregions of the SNr, i.e., lateral SNr and medial SNr.
Introduction: There is a paucity of information related to treatment of pediatric CRPS. Treatment of CRPS in pediatric patients has been guided by adult recommendations which consists of a multidisciplinary approach of pharmacotherapy, physical therapy, and psychotherapy, as appropriate. Patients unable to tolerate physical therapy with traditional oral pharmacotherapy may require more invasive pain management techniques.
In order to reach the research goals, 28 individuals with Parkinson's disease under deep brain stimulation were randomly assigned into two groups including Dexmedetomidine and Propofol that referring to Shohada Tajrish Hospital in 2016 . The following drugs were used: Dexmedetomidine with dose of 0.2-0.4 μ/kg/h and Propofol with doses of 20-30 mg bolus, and then 10-20 μ/kg/min infusion, with a control and preservation of BIS between 65 and 85. The total dose of local anaesthetic drugs was recorded at the end of the procedure.
Patients with severe mental illness experience greater morbidity and mortality than the general population, in part because of differences in the provision of necessary medical care.1 At times, this can be due to agitation, catatonia, impaired capacity, or persistent symptoms that contribute to ongoing morbidity and may prevent performance of necessary diagnostic procedures. In such situations, performing procedures under general anesthesia may be the only safe way to provide essential care to an already vulnerable patient.
Attempts at neuromodulation using deep brain stimulation (DBS) have targeted a number of loci in brain arousal pathways such as the thalamus, mesencephalon and cervical cord. However, recovery following single location stimulation remains modest, especially in comatose patients. Although some of these pathways can trigger awakening from sleep or light planes of anesthesia upon activation are insufficient to promote arousal from a deeper arousal state like coma. Interpretation of these results suggests that to fully emerge from a deep arousal state, coordination of multiple pathways is required.
Research and clinical studies report that ketamine has rapid and sustained antidepressant effects. Low-dose ketamine infusion could affect a number of cortical and limbic brain regions, many of which are reported to show alterations of glutamate transmission and synaptic plasticity.
Traumatic spinal cord injury (SCI) results in loss of sensorimotor functions below the level of injury besides other secondary complications such as pain. However, regardless of many efforts, management of the SCI patients is difficult. In the present study, we used a non-invasive and easy to implement extremely low-frequency electromagnetic field (ELF-EMF; 50 Hz, 17.96 μT) technique to stimulate whole body after SCI. Laminectomy was performed at T10-12 vertebrae (Sham group) in anesthetized adult male rat followed by complete transection of the spinal cord at T11 vertebra and then half of the rats were subsequently exp...
Conventional transcranial ultrasound stimulation (tUS) for animal studies utilize external bulky transducer systems, requiring the use of wires that limit the study to anesthetized or immobilized subjects. To facilitate behavioral studies with ultrasound, we designed a portable wireless tUS system that can provide acoustic stimulation on a freely behaving rat. Stimulation is given by a transducer attached on the rat skull that is driven by a circuit placed on the back of the rat. The whole system is controlled wirelessly via bluetooth.
Background: The time interval between anaesthetic induction and ECT stimulus administration is one aspect of treatment technique that has not been thoroughly examined until recently. This variable is easily monitored and manipulated, and may represent an indirect measure of anaesthetic concentration at the time of stimulation. Importantly, the anaesthetic-ECT time interval may influence the quality of ictal EEG traces observed and could thereby influence dosing decisions.