The Cluster of Abnormalities Related to Metabolic Syndrome Is Associated With Reduced Glomerular Filtration Rate and Raised Albuminuria in Patients With Type 2 Diabetes Mellitus.
The Cluster of Abnormalities Related to Metabolic Syndrome Is Associated With Reduced Glomerular Filtration Rate and Raised Albuminuria in Patients With Type 2 Diabetes Mellitus. J Clin Med Res. 2017 Sep;9(9):759-764 Authors: Kurata M, Takenouchi A, Tsuboi A, Minato S, Takeuchi M, Kitaoka K, Fukuo K, Kazumi T Abstract BACKGROUND: As association of metabolic syndrome (MS) with chronic kidney disease (CKD) has not been extensively studied in patients with type 2 diabetes, we addressed these issues. METHODS: Intrapersonal means of 12 measurements of waist circumference, blood pressure and high-density lipoprotein (HDL) cholesterol and those of six measurements of fasting triglycerides during 12 months were calculated in a cohort of 168 previously reported Japanese patients with type 2 diabetes. Based on these means, MS was diagnosed according to the modified National Cholesterol Education Program Adult Treatment Panel III criteria with the Asian definition of abdominal obesity. CKD was defined as the presence of low estimated glomerular filtration rate (eGFR
Publication date: Available online 31 March 2020Source: Materials Today: ProceedingsAuthor(s): K. Senthil Kannan, S. Gayathri Devi, Prithiviraj Nagarajan, G. Flora, R. Ranadevan
Publication date: Available online 31 March 2020Source: Clinica Chimica ActaAuthor(s): Tomoyuki Kawada
Authors: Kamimura MA, Nerbass FB PMID: 32227070 [PubMed - as supplied by publisher]
Authors: Ventura CG, Roque FL, Sousa IQ, Lobo RD, Luders C Abstract INTRODUCTION: Chronic hemodialysis (HD) patients are considered to be at high risk for infection. Here, we describe the clinical outcomes of chronic HD patients with influenza A (H1N1) infection and the strategies adopted to control an outbreak of influenza A in a dialysis unit. METHODS: Among a total of 62 chronic HD patients, H1N1 infection was identified in 12 (19.4%). Of the 32 staff members, four (12.5%) were found to be infected with the H1N1 virus. Outcomes included symptoms at presentation, comorbidities, occurrence of hypoxemia, hospit...
Org. Biomol. Chem., 2020, Advance Article DOI: 10.1039/D0OB00437E, PaperMaina Takahashi, Junya Shirasaki, Naoko Komura, Katsuaki Sasaki, Hide-Nori Tanaka, Akihiro Imamura, Hideharu Ishida, Shinya Hanashima, Michio Murata, Hiromune Ando GM3 gangliosides have been synthesizedvia late-stage α-sialylation using a macro-bicyclic sialyl donor.19F solid-state NMR analysis of the C5-NHTFAc GM3 analog on a model membrane revealed the influence of cholesterol on glycan dynamics. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
CONCLUSION: TT extract and its saponin fraction exerted anti-inflammatory effects on HUVEC and HBMEC lines and reduced the expression of ICAM-1, VCAM-1, and E-selectin. However, the anti-inflammatory effect of aqueous extract was greater than that of saponin fraction. Therefore, TT could be considered as a potential candidate for the treatment or prevention of atherosclerosis. PMID: 32224542 [PubMed - in process]
Publication date: Available online 31 March 2020Source: Life SciencesAuthor(s): J.D. Villeda-González, J.L. Gómez-Olivares, L.A. Baiza-Gutman, L. Manuel-Apolinar, L. Damasio-Santana, Cesar Millán-Pacheco, Selene Ángeles-Mejía, M.C. Cortés-Ginez, M. Cruz-López, C.J. Vidal-Moreno, M. Díaz-Flores
Proportion is far higher than those found in clinical trials of the cancer drugs; study finds differences by cancer type.Medscape Medical News
Authors: Tomita H PMID: 32224558 [PubMed - as supplied by publisher]
Purpose of review The goal of this review is to present recent models of the filtration barrier that may suggest mechanism-based treatments for proteinuric renal disease. The vast majority of renal failure occurs in diseases of glomerular proteinuria. The physiology of the filtration barrier remains incompletely understood, preventing invention of mechanism-based therapies. Research is currently dominated by molecular biology approaches to the kidney instead of engineering-based filtration and transport models. Recent findings Reexamination of two older paradigms (basement membrane and slit diaphragm) and critical ana...