Absence of CX3CR1 impairs the internalization of Tau by microglia

Extracellular Tau is toxic for neighboring cells, and it contributes to the progression of AD. The CX3CL1/CX3CR1 axis is an important neuron/microglia communication mechanism.

Source: Molecular Neurodegeneration - August 15, 2017 Category: Neurology Authors: Marta Bol ós, María Llorens-Martín, Juan Ramón Perea, Jerónimo Jurado-Arjona, Alberto Rábano, Félix Hernández and Jesús Avila Tags: Research article Source Type: research