The expression of endogenous hydrogen sulfide signal during distraction osteogenesis in a rabbit model

The hydrogen sulfide (H2S) signal system plays an important role in bone metabolism. However, the role of endogenous H2S during distraction osteogenesis (DO) remains unclear. Sixty-two male New Zealand White rabbits were subjected to right mandibular DO. Before distraction, the animals were divided randomly into two groups: group A, 0.5mm twice/day for 10 days; group B, 1.25mm twice/day for 4 days. Plasma and distraction gap tissue were harvested to determine the H2S signal. The osteogenesis effect was also evaluated.

Source: International Journal of Oral and Maxillofacial Surgery - August 14, 2017 Category: ENT & OMF Authors: X.-W. Jiang, Y. Zhang, Y.-Z. Cheng, X.-S. Fan, X. Deng, H.-Y. Peng Tags: Research Paper Source Type: research