How Gata4 helps mend a broken heart

(Baylor College of Medicine) Gata4 alone is able to reduce post-heart attack fibrosis and improve cardiac function in a rat model of heart attack. In rat fibroblasts in the lab, the molecular mechanism involves reduced expression of Snail, the master gene of fibrosis.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news