Author response: Hyperbaric oxygen: B-Level evidence in mild traumatic brain injury clinical trials
We thank Drs. Hampson and Holm for commenting on our Views &Reviews article.1 It is true that PaO2 was not measured in the published studies and assumptions were made regarding normal metabolism and pulmonary function of the study participants. This was a valid assumption, as all participants were cleared to be placed inside a pressure vessel and not excluded due to pulmonary or metabolic dysfunctions.
Surg Technol Int. 2021 Jul 29;39:sti39/1456. Online ahead of print.ABSTRACTOver the past three decades, there has been a growing interest in the use of oxygen therapy to promote wound healing. Although the most commonly recognized oxygen therapy for the treatment of chronic wounds is hyperbaric oxygen therapy, topical oxygen therapy has a greater level of evidence supporting its use in chronic wound care. Still, it is imperative that these two treatment modalities be recognized not merely as competitors, but as distinct therapeutic entities. Through personal experience and a thorough literature review, we investigated the ...
Spinal Cord, Published online: 29 July 2021; doi:10.1038/s41393-021-00674-wEffects of hyperbaric oxygen therapy on postoperative recovery after incomplete cervical spinal cord injury
ConclusionHBOT has the potential to be a very useful adjunct in the treatment of osteomyelitis in head and neck surgery; however, there is a need for carefully designed trials, avoiding methodological bias due to the great variability of patients, infectious agents, antibiotic resistance, host factors, to broaden the evidence of this therapeutic modality.
Hyperbaric Oxygen Therapy (HBOT) devices only considered safe and effective for certain conditions. The FDA recommends you use a HBOT device under the care of a doctor and in a hospital or facility that has hyperbaric accreditation.
No abstract available
Multiple surgeries on patients born with bladder exstrophy and epispadias (BEE) especially when complicated by postoperative infections results in varying degrees of scarring of the tissues and decreased vascularity. When further surgery for these patients is contemplated the tissue ischemia may result in poor healing and additional complications. Problem wounds due to arterial insufficiency mainly in diabetic ulcers and following therapeutic radiation are commonly treated with hyperbaric oxygen therapy (HBOT).
ConclusionsHBO’s repression of the Warburg effect, repression of hyperproliferation, and repression of EMT in hypoxic NSCLC cells is dependent upon HIF-1α downregulation. HIF-1α’s target gene PFKP functions as a central mediator of HBO’s effects in hypoxic NSCLC cells and may represent a metabolic vulnerability in NSCLC tumors.
AbstractBreast cancer is a multifactorial, heterogeneous disease and the second most frequent cancer amongst women worldwide. Metastasis is one of the most leading causes of death in these patients. Early-stage or locally advanced breast cancer is limited to the breast or nearby lymph nodes. When breast cancer spreads to farther tissues/organs from its original site, it is referred to as metastatic or stage IV breast cancer. Normal breast development is regulated by specific genes and signalling pathways controlling cell proliferation, cell death, cell differentiation and cell motility. Dysregulation of genes involved in v...
CONCLUSION: The association of oxygen therapy in a hyperbaric chamber with the conventional protocol for treating vascular occlusion from facial filler procedures was found to be effective.PMID:34263009 | PMC:PMC8253178 | DOI:10.1080/23320885.2021.1933492
ConclusionsELO water raises arterial blood oxygen levels, appears to have a protective effect on hyperglycaemia-induced reduction in mitochondrial mass and mitochondrial dysfunction, and may be effective adjuvant therapy for type 2 diabetes.