Effects of exercise on fitness and health of adults with spinal cord injury: A systematic review

Conclusions: Exercise improves fitness and cardiometabolic health of adults with chronic SCI. The evidence on effective exercise types, frequencies, intensities, and durations should be used to formulate exercise guidelines for adults with SCI.
Source: Neurology - Category: Neurology Authors: Tags: Clinical trials Systematic review/meta analysis, All Rehabilitation, All Spinal Cord VIEWS & amp;amp; REVIEWS Source Type: research

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AbstractCervical spinal cord injury (SCI) can cause tetraplegia. Nerve transfer has been routinely utilized for reconstruction of hand in brachial plexus injuries. Here, we report reconstruction of finger flexion (hand grasp) and extension (hand release) in a victim of cervical spinal cord injury with tetraplegia. We also focus on importance of extension phase in restoration of hand function in the tetraplegic case, in addition to provision of a detailed description of both operations including text, photographs, and a video. We used double nerve transfer, namely brachialis branches of musculocutaneous nerve to anterior in...
Source: Acta Neurochirurgica - Category: Neurosurgery Source Type: research
I read with great interest the study recently published by Yamanaka and colleagues,1 reporting the results of the study aimed to pharmacologically induce β common receptor (βcR) subunit upregulation before ischemia to optimize the neuroprotective effect of erythropoietin (EPO). The authors hypothesized that βcR subunit upregulation by diazoxide (DZ) before ischemia amplifies the neuroprotective effects of EPO in mice after spinal cord injury (SCI) . They reported that that optimal βcR upregulation occurred at 36 hours after DZ administration, and the optimal DZ dosage for βcR induction was 20 mg/kg.
Source: The Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Adult: Aorta: Letter to the Editor Source Type: research
Developmental Dynamics,Volume 0, Issue ja, -Not available-.
Source: Developmental Dynamics - Category: Molecular Biology Authors: Source Type: research
Publication date: Available online 14 October 2018Source: NeuroscienceAuthor(s): Qian Chen, Weimin Zheng, Xin Chen, Xuejing Li, Ling Wang, Wen Qin, Kuncheng Li, Nan ChenAbstractVisual-related cortex plays an important role in the process of movement. It is great of importance to clarify whether traumatic spinal cord injury (SCI), which is a typical disease resulted in sensorimotor dysfunction, leads to the alteration of visual-related brain structure and function area. To address this issue, multimodality MRI was applied on eleven patients with acute incomplete cervical cord injury (ICCI) and eleven healthy controls (HCs) ...
Source: Neuroscience - Category: Neuroscience Source Type: research
Journal of Cellular Biochemistry, EarlyView.
Source: Journal of Cellular Biochemistry - Category: Biochemistry Authors: Source Type: research
Authors: Zhu L Abstract Despite more than 80 years of animal experiments and clinical practice, efficacy of hypothermia in improving treatment outcomes in patients suffering from cell and tissue damage caused by ischemia is still ongoing. This review will first describe the history of utilizing cooling in medical treatment, followed by chemical and biochemical mechanisms of cooling that can lead to neuroprotection often observed in animal studies and some clinical studies. The next sections will be focused on current cooling approaches/devices, as well as cooling parameters recommended by researchers and clinicians...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Authors: Wang H, Song G, Chuang H, Chiu C, Abdelmaksoud A, Ye Y, Zhao L Abstract Fibrosis is formed after injury in most of the organs as a common and complex response that profoundly affects regeneration of damaged tissue. In central nervous system (CNS), glial scar grows as a major physical and chemical barrier against regeneration of neurons as it forms dense isolation and creates an inhibitory environment, resulting in limitation of optimal neural function and permanent deficits of human body. In neurological damages, glial scar is mainly attributed to the activation of resident astrocytes which surrounds the l...
Source: International Journal of Immunopathology and Pharmacology - Category: Allergy & Immunology Tags: Int J Immunopathol Pharmacol Source Type: research
CONCLUSIONS: Under a similar increase in core temperature, ΔIL-6% was lower in the CSCI group compared with the AB group. These findings suggest that the observed rise in IL-6 during hyperthermia is mediated, at least in part, by plasma adrenaline. PMID: 30303416 [PubMed - as supplied by publisher]
Source: International Journal of Hyperthermia - Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research
Authors: Hayashida KI, Eisenach JC Abstract Gabapentinoids are effective in a wide range of animal pain models and in patients with neuropathic pain and has become one of first-line treatments for neuropathic pain. Because spinal plasticity and sensitization have been intensely studied in neuropathic pain, most laboratory studies have focused on actions of gabapentinoids in the spinal cord, where they reduce primary afferent traffic and excitation of spinal nociceptive neurons, via interaction with α2δ subunits of voltage-gated Ca2+ channels. However, a recent clinical study questioned the relevance of ...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Source: Journal of Sports Sciences - Category: Sports Medicine Authors: Source Type: research
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