MRI evidence of acute inflammation in leukocortical lesions of patients with early multiple sclerosis

Conclusions:
The presence of enhancing lesions affecting the cortex and adjacent white matter, although transient and not frequent, suggests that at least some cortical lesions are related to blood–brain barrier disruption. Our data support the concept that there may be an acute inflammatory phase in the development of leukocortical MS lesions.

Clinicaltrials.gov identifier:
NCT00176592.

Source: Neurology - August 14, 2017 Category: Neurology Authors: Maranzano, J., Rudko, D. A., Nakamura, K., Cook, S., Cadavid, D., Wolansky, L., Arnold, D. L., Narayanan, S. Tags: MRI, Multiple sclerosis ARTICLE Source Type: research