Fragility of epidermis: acne and post ‐procedure lesional skin

We present epidemiological data on the prevalence of fragile skin in three different geographical regions, and the results of two randomized controlled studies investigating the efficacy and tolerability of dermo‐cosmetics in combination with topical acne treatment and following physical skin damage. Overall, we found that prevalence across the three regions (23% in Germany, 41% in UAE, 56% in Taiwan) reflected previous global estimates (24–53%) across skin types, with significant associations found with environmental and lifestyle factors, such as stress, humidity and pollution. The iatrogenic effects of topical acne treatments can result in poor compliance or use of over‐the‐counter moisturizers, which may reduce treatment efficacy. Dermo‐cosmetics were found to aid in restoration of fragile skin caused by the acne topical retinoid treatment adapalene 0.1% gel, by reducing transepidermal water loss and improving skin hydration, as well as reducing the side‐effects such as skin irritation that are frequently associated with topical retinoids. Additionally, dermo‐cosmetic products were found to accelerate wound closure following skin damage in a laser ablation model and reduced the duration of post‐procedural side‐effects such as itching and burning.
Source: Journal of the European Academy of Dermatology and Venereology - Category: Dermatology Authors: Tags: Original Article Source Type: research