Neurodegenerative disease: Citalopram drives down amyloid-β

Nature Reviews Drug Discovery 13, 496 (2014). doi:10.1038/nrd4378 Author: Charlotte Harrison Serotonin signalling suppresses the production of amyloid-β (Aβ) in animal models of Alzheimer's disease. Sheline et al. showed that the antidepressant citalopram — a selective serotonin reuptake inhibitor — prevented the growth of pre-existing Aβ plaques and reduced the appearance of new plaques in
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Research Highlight Source Type: research