Prognostic Value of Circulating Amino Acids (Aas) in Patients with Idiopathic Dilated Cardiomyopathy (DCM)

Background: Circulating levels of some amino acids are significantly decreased in heart failure patients. However, relationship between their levels and cardiac function remains unclear. We therefore examined association between amino acid levels and cardiac function as prognostic predictor in DCM patients. Methods: Consecutive 60 patients with DCM (M/F: 47/13, mean age: 59 years) were enrolled. We measured 25 kinds of plasma AA concentration, derivative of reactive oxygen metabolites (d-ROMs) as marker of oxidative stress, and washout rate of Tc-99m Sestamibi (WOR) as function of mitochondria and LVEF as LV function parameters.
Source: Journal of Cardiac Failure - Category: Cardiology Authors: Source Type: research