Implication of endoplasmic reticulum stress and mitochondrial dysfunction in abdominal aortic aneurysm disease

Aim: Aim: Clinical management of abdominal aortic aneurysm (AAA) is limited to elective surgical repair while an effective pharmacotherapy is awaited. We aimed to elucidate the involvement of endoplasmic reticulum (ER) and mitochondrial stress in vascular wall degeneration during the development of AAA.

Source: Atherosclerosis - August 1, 2017 Category: Cardiology Authors: Miquel Navas Madro ñal, Jose Roman Escudero, Luis Vila, Jose Martinez Gonzalez, Mercedes Camacho, Cristina Rodriguez, Maria Galan Source Type: research