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Americans want a say in human genome editing, survey shows

When it comes to CRISPR, our society has some important decisions to make.Just last week, scientistsreported a new first in the journal Nature: They edited heritable cells in human embryos to treat an inherited form of heart disease. The day after the research was published, a group of genetics...
Source: Los Angeles Times - Science - Category: Science Authors: Source Type: news

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(Reuters Health) - Brain scans obtained during psychological stress might someday help doctors identify people who are at higher risk for heart disease, a new study suggests.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Authors: Li CL, Niu L, Fu MY, Tian J, Wang QW, An XJ Abstract OBJECTIVE: To analyze the links between NFATC1 gene polymorphism and congenital heart disease in children. PATIENTS AND METHODS: In the present study, we selected 85 children patients with congenital heart disease who were hospitalized from February 2013 to February 2015 as research subjects (observation group), and 92 healthy subjects as control group. Restriction fragment length polymorphism (RFLP) was used for analysis of NFATC1 gene in samples from each group. RESULTS: The distribution of NFATC1 genotype and allele between the observation gro...
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Most of us already notice obvious changes in our bodies such as body weight, blood pressure, and waist circumference. During the Undoctored process you will discover that you could also benefit from tracking some important lab values. These lab values will reflect reemerging health in blood sugar levels, triglycerides, and factors that reflect risk for heart disease, stroke, and other conditions. Here are lab values to consider tracking: Fasting glucose, hemoglobin A1c, fasting insulin—all reflecting blood sugar and insulin-resistance status NMR lipoproteins (NMR LipoProfile) or other advanced lipoprotein testing ...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: News & Updates Source Type: blogs
Conclusion: To address the many challenges posed by EDCs, we argue that Africans should take the lead in prioritization and evaluation of environmental hazards, including EDCs. We recommend the institution of education and training programs for chemical users, adoption of the precautionary principle, establishment of biomonitoring programs, and funding of community-based epidemiology and wildlife research programs led and funded by African institutes and private companies. https://doi.org/10.1289/EHP1774 Received: 16 February 2017 Revised: 22 May 2017 Accepted: 24 May 2017 Published: 22 August 2017 Address correspond...
Source: EHP Research - Category: Environmental Health Authors: Tags: Commentary Source Type: research
ConclusionsA significant proportion of the Iranian population, based on FRS model, will be at moderate to high risk of coronary events in the next 10  years. Urgent preventive plans are needed at the national level.
Source: Journal of Diabetes and Metabolic Disorders - Category: Endocrinology Source Type: research
Publication date: 22 August 2017 Source:Cell Reports, Volume 20, Issue 8 Author(s): Fabio Da Silva, Ana Sofia Rocha, Fariba Jian Motamedi, Filippo Massa, Cem Basboga, Harris Morrison, Kay Dietrich Wagner, Andreas Schedl Coronary arteries are essential to support the heart with oxygen, and coronary heart disease is one of the leading causes of death worldwide. The coronary arteries form at highly stereotyped locations and are derived from the primitive vascular plexus of the heart. How coronary arteries are remodeled and the signaling molecules that govern this process are poorly understood. Here, we have identified the Wn...
Source: Cell Reports - Category: Cytology Source Type: research
Nature advance online publication 23 August 2017. doi:10.1038/nature23544 Author: Sekar Kathiresan Molecules that block the activity or production of the protein ANGPTL3 have now been found to lower blood levels of lipoproteins and cholesterol in mice and healthy humans, mimicking the protective effects of genetic mutations in ANGPTL3.
Source: Nature AOP - Category: Research Authors: Tags: News & Views Source Type: research
Hopkins Nursing—Dean on Immunization / New Faculty / Saudi Arabian DNP Graduates body,#bodyTable,#bodyCell{ height:100% !important; margin:0; padding:0; width:100% !important; } table{ border-collapse:collapse; } img,a img{ border:0; outline:none; text-decoration:none; } h1,h2,h3,h4,h5,h6{ margin:0; padding:0; } p{ margin:1em 0; padding:0; } a{ word-wrap:break-word; } .mcnPreviewText{ display:none !important; } .ReadMsgBody{ width:100%; } .ExternalClass{ width:100%; } .ExternalClass,.ExternalClass p,.ExternalClass span,.Externa...
Source: Johns Hopkins University and Health Systems Archive - Category: Nursing Source Type: news
This is an update of a post from November 2015.If you are doing a systematic review, you will need to run the same search in more than one database.I use the term " translation " for the process of modifying a search so that it works in another database.It is important to run the same search in all databases.So, if you have a search that works in Ovid Medline, what do you need to change to make it work in another database like PsycINFO or Embase?  Those other databases have different features or functionality.There are three areas where translation is necessary, once you have finalised your strategy:Search s...
Source: Browsing - Category: Databases & Libraries Source Type: blogs
CONCLUSIONS: Patients with congenital heart disease and PAH have significant morbidity and mortality. PAH is more prevalent in patients with Down syndrome. While pulmonary pressure during the reproductive years was not always known, 27% of women with PAH at the time of the study were multiparous. PMID: 28825767 [PubMed - in process]
Source: The Israel Medical Association Journal - Category: General Medicine Tags: Isr Med Assoc J Source Type: research
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