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Americans want a say in human genome editing, survey shows

When it comes to CRISPR, our society has some important decisions to make.Just last week, scientistsreported a new first in the journal Nature: They edited heritable cells in human embryos to treat an inherited form of heart disease. The day after the research was published, a group of genetics...
Source: Los Angeles Times - Science - Category: Science Authors: Source Type: news

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In this report, we describe the first case, to our knowledge, of congenital Zika syndrome with concomitant critical congenital heart disease. The mother had a confirmed ZIKV infection in the first trimester of pregnancy. Fetal ultrasonography at 31 weeks of gestation revealed cerebral cortical calcifications and hypoplastic left heart syndrome. The severity of brain involvement was assessed by postnatal magnetic resonance imaging and echocardiogram, and palliative surgery was performed. The ethical dimensions of this infant's clinical management are discussed. ZIKV is known to affect neural progenitor cells, but whether it...
Source: Neonatology - Category: Perinatology & Neonatology Source Type: research
CONCLUSIONS: Most patients hospitalized for NVAF were discharged to home support, and the majority did not have OAC treatment during hospitalization or the 30 days post-discharge. Additional investigation should be conducted on trends beyond 30 days post hospitalization and the reasons for not receiving anticoagulation therapy in patients at moderate to severe risk of stroke or systemic embolism. Helping to avoid preventable strokes is an important goal for public health. PMID: 29235900 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
Calcific aortic stenosis (AS) is the most frequent valvular heart disease in developed countries [1]. Aortic valve calcification (AVC) burden measures lesion severity in AS and is useful for diagnostic and prognostic purposes. Indeed: 1. AVC is strongly but nonlinearly associated with hemodynamic measures of AS severity [2]; 2. AVC can help to discriminate severe from nonsevere AS in patients with discordant echocardiographic findings (normal flow-low gradient and low flow-low gradient AS with small valve area); and 3.
Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Editorial Source Type: research
In this study, we investigated the prevalence of TA in young women presenting with IHD in the Emergency Department.
Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Short communication Source Type: research
Authors: Ban JE Abstract Arrhythmias in the neonatal period are not uncommon, and may occur in neonates with a normal heart or in those with structural heart disease. Neonatal arrhythmias are classified as either benign or nonbenign. Benign arrhythmias include sinus arrhythmia, premature atrial contraction, premature ventricular contraction, and junctional rhythm; these arrhythmias have no clinical significance and do not need therapy. Supraventricular tachycardia, ventricular tachycardia, atrioventricular conduction abnormalities, and genetic arrhythmia such as congenital long-QT syndrome are classified as nonbeni...
Source: Korean Journal of Pediatrics - Category: Pediatrics Tags: Korean J Pediatr Source Type: research
Conclusion Differences in age, gender, and CVD independently affect AAS. The lower AAS observed in ToF fosters its assessment during follow-up in adulthood. Future studies on causes and clinical implications of a higher AAS in females affected by ToF are warranted.
Source: European Journal of Radiology - Category: Radiology Source Type: research
CHILDREN who eat takeaways at least once a week are more likely to develop heart disease and diabetes later in life, according to new research.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Conclusions: The results suggested that the expression of miR-126-enhanced ADSC-derived exosomes prevented myocardial damage by protecting myocardial cells from apoptosis, inflammation, fibrosis, and increased angiogenesis.Cell Physiol Biochem 2017;44:2105 –2116
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research
Rural areas face higher rates of chronic disease and higher related mortality rates. In some rural regions of the country and for some rural population groups, the disparity is even worse. The Rural Health Information Hub announces a new guide which discusses the impact of chronic disease on rural America, how providers and communities can help patients with chronic diseases, and where to look for funding to establish programs to address chronic conditions. The guide provides an overview of chronic disease generally as well as specific conditions, including heart disease and stroke, cancer, diabetes, chronic...
Source: BHIC - Category: Databases & Libraries Authors: Tags: Chronic Disease Rural Source Type: blogs
Cardiovascular artificial intelligence medtech firm Bay Labs said today it raised $5.5 million in a Series A round to support clinical validation and further development of its cardiovascular imaging tech. The round was led by existing investor Khosla Ventures and joined by newly invested Data Collective, Greenbox Venture Partners, Minneapolis Heart Institute Ventures and Georges Harik. As part of the funding round, Khosla Ventures general partner Ben Ling and DCVC operating partner Armen Vidian will join the San Francisco-based company’s board of directors. “Bay Labs’ unique application of AI with ultras...
Source: Mass Device - Category: Medical Devices Authors: Tags: Business/Financial News Cardiovascular Imaging Software / IT baylabs Source Type: news
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