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Type 2 diabetes rise in children 'disturbing'

More than 600 children and teenagers are being treated for the condition in England and Wales, experts warn.
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news

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Source: Journal of Pineal Research - Category: Research Authors: Tags: Original Article Source Type: research
Moving along the treadmill of life, many of us succumb to the ever-present pressures to be faster, stronger, more efficient, and smarter. Perspective on what is happening in our lives is lost. We focus on failure and lacking within ourselves, rather than the abundance and opportunities for growth that surround us. We stop taking the time to appreciate the simple pleasures of our lives as we spiral our way into a depleted existence — physically, emotionally, and mentally. Now more than ever, there is a global need to circumvent this pattern of being. We need to learn to unconditionally love and appreciate ourselves ju...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Brain Blogger Creativity Happiness Inspiration & Hope Mindfulness Motivation and Inspiration Publishers Journaling Meditation Mindfulness Meditation Perspective Self-reflection well-being Source Type: blogs
Authors: Yanase T, Yanagita I, Muta K, Nawata H Abstract Frailty is a state of vulnerability and a consequence of cumulative decline in multiple physiological systems over a lifespan. The occurrence of frailty depends on deterioration in muscle and nerve function, declining cardiopulmonary reserve and loss of executive function. Diabetes mellitus (DM) often causes functional impairment in each of the above systems, thus leading to a loss of whole body homeostasis and deterioration in physical function. Inability of self-management in DM patients may also have considerable impact on the development of sarcopenia/fra...
Source: Endocrine Journal - Category: Endocrinology Tags: Endocr J Source Type: research
This study was conceived to explore the possible mechanisms of how hyperuricemia and obesity contribute to renal function impairment in type 2 diabetic (T2DM) patients. A cross-sectional study in 609 participants recruited from a T2DM population in North China was conducted. The multiplicative interaction between body mass index (BMI) and uric acid (UA) level was assessed using an interaction term in a logistic regression analysis. Our results indicate that male T2DM patients having higher BMI (OR 1.711, p = 0.038), blood urine nitrogen (BUN) (OR 1.100, p = 0.034), and 24-hour urinary micro-albumin levels (OR 1.004, p = 0....
Source: Endocrine Journal - Category: Endocrinology Tags: Endocr J Source Type: research
Also in this edition: How media literacy can help combat conspiracy theories; lifestyle vs. drugs in Type 2 diabetes prevention; and plants can actually be sedated.
Source: CBC | Health - Category: Consumer Health News Tags: News/Health Source Type: news
CONCLUSION: Time to diagnosis of CN was shorter than previously reported, though the high rate of deformities still suggests a significant delay in diagnosis. Increased education of healthcare professionals and people with diabetes-related neuropathy is important to ensure early diagnosis and appropriate management to reduce deformities and complications. PMID: 29240741 [PubMed - in process]
Source: New Zealand Medical Journal - Category: General Medicine Tags: N Z Med J Source Type: research
Publication date: 12 December 2017 Source:Cell Reports, Volume 21, Issue 11 Author(s): Anthony R. Soltis, Norman J. Kennedy, Xiaofeng Xin, Feng Zhou, Scott B. Ficarro, Yoon Sing Yap, Bryan J. Matthews, Douglas A. Lauffenburger, Forest M. White, Jarrod A. Marto, Roger J. Davis, Ernest Fraenkel Obesity is a major human health crisis that promotes insulin resistance and, ultimately, type 2 diabetes. The molecular mechanisms that mediate this response occur across many highly complex biological regulatory levels that are incompletely understood. Here, we present a comprehensive molecular systems biology study of hepatic respo...
Source: Cell Reports - Category: Cytology Source Type: research
AbstractObjectiveThe study investigated the use of great curvature plication with duodenal –jejunal bypass (GCP-DJB) in a type 2 diabetic with obesity rat model.MethodsTwenty-two Sprague-Dawley rats were given a high fat and sugar diet with subsequent intraperitoneal injection of a small dosage of streptozotocin (30  mg/kg) and randomly assigned to either GCP-DJB (n = 12) or Sham surgery (n = 10). Body weight, peripheral blood glucose, and fasting serum insulin were assayed, and insulin resistance index (IRI) was calculated, before and at 1, 2, 4, and 8 weeks after surgery.Result...
Source: Obesity Surgery - Category: Surgery Source Type: research
ConclusionSmoking and weight gain were factors that decreased the effect of sitagliptin on reducing blood glucose levels. Differences in concomitant drugs did not affect sitagliptin ’s effects on glycemic control. A dose increase or the addition of the antidiabetic drug was not associated with concomitant drugs.
Source: Diabetology International - Category: Endocrinology Source Type: research
Conclusion The plasma homocysteine concentrations were inversely correlated with T2DM among a middle-aged and elderly Chinese population.
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
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