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MassDevice.com +5 | The top 5 medtech stories for August 11, 2017

Say hello to MassDevice +5, a bite-sized view of the top five medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 5 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry. Get this in your inbox everyday by subscribing to our newsletters.   5. This 3D printed implant replaces skull bone A New Jersey doctor turned to Johnson &Johnson’s DePuy Synthes and a 3D printed implant to replace missing skull bone in a patient. The procedure was performed after the patient suffered brain swelling and the skull became infected. Dr. Gaurav Gupta, assistant professor of neurosurgery at Rutgers Robert Wood Johnson Medical School, had to perform emergency surgery on Chris Cahill after he was suffering from life threatening brain swelling in the frontal lobe. Gupta relieved the pressure and intended on replacing the skull once the swelling went down, but the skull became infected and was unusable. His solution was to use 3D printing to replace the missing skull bone. Read more 4. EnteroMedics prices $20m preferred stock offering EnteroMedics today priced an upcoming underwritten public offering looking to raise $20 million to support continued commercialization and product development. In the offering, the company will offer units at $1,000 per unit, with each consisting of 1 share of Series B convertible preferred stoc...
Source: Mass Device - Category: Medical Devices Authors: Tags: News Well Plus 5 Source Type: news

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Here we report a successful percutaneous endovascular retrieval of a VenaTech LP inferior vena cava (IVC) filter (B. Braun, Evanston, Illinois) that had migrated to the right ventricle in a morbidly obese patient who presented with chest pain. Case reports such as this are exempt from institutional review board approval.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Special Letter Section Source Type: research
Conclusions: The present study has confirmed high levels of overweight and obesity in Maltese children. It also provides proof of concept of scalability by demonstrating the feasibility of undertaking a relatively inexpensive study of an entire childhood population. The modus operandi (utilizing physical education teachers) could relatively easily be up scaled for any country.
Source: Journal of Pediatric Gastroenterology and Nutrition - Category: Gastroenterology Tags: Original Articles: Nutrition Source Type: research
In this study, we evaluated effects of O. gratissimum extract (OGE) in preventing obesity by using ovariectomized (OVX) animal models to mimic menopausal women. Methods: OVX rats showed increase in body weight and in adipocyte size in perigonadal adipose tissue (p
Source: International Journal of Medical Sciences - Category: Biomedical Science Tags: Int J Med Sci Source Type: research
Authors: Pérez-Belmonte LM, Moreno-Santos I, Gómez-Doblas JJ, García-Pinilla JM, Morcillo-Hidalgo L, Garrido-Sánchez L, Santiago-Fernández C, Crespo-Leiro MG, Carrasco-Chinchilla F, Sánchez-Fernández PL, de Teresa-Galván E, Jiménez-Navarro M Abstract Epicardial adipose tissue has been proposed to participate in the pathogenesis of heart failure. The aim of our study was to assess the expression of thermogenic genes (Uncoupling protein 1 (UCP1), peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1α), and PR-domain-missing 16 (...
Source: International Journal of Medical Sciences - Category: Biomedical Science Tags: Int J Med Sci Source Type: research
Conclusion: PBMCs β2AR, underexpressed in centrally obese, are associated with a better metabolic profile and showed a protective role for the development of CO. The discovery of β2AR as a new molecular marker of obesity subphenotypes in PBMCs might contribute to clarify the adrenergic immunomodulation of inflammatory obesity. PMID: 28824322 [PubMed - in process]
Source: International Journal of Medical Sciences - Category: Biomedical Science Tags: Int J Med Sci Source Type: research
Authors: Manco M, Nobili V, Alisi A, Panera N, Handberg A Abstract Atherosclerosis origins early in childhood. Aim of the study was to investigate vascular signature and phenotypes of cardiovascular disease in obese children and adolescents identifying novel potential circulating markers of risk. Cross-sectional study of intima-media-thickness (IMT), pulse wave velocity (PWV), augmentation index (AIX@75), circulating markers (E-selectin, soluble-intercellular-adhesion-molecule1_ICAM1, chemerin, fatty-acid-binding protein 4, sCD36, lipopolysaccharides_LPS, oxLDL, fetuin) in 123 obese (body mass index, BMI z-score>...
Source: International Journal of Medical Sciences - Category: Biomedical Science Tags: Int J Med Sci Source Type: research
Authors: Savas M, Wester VL, Staufenbiel SM, Koper JW, van den Akker ELT, Visser JA, van der Lely AJ, Penninx BWJH, van Rossum EFC Abstract Background: Although the use of corticosteroids has been linked to high incidence of weight gain, no data are available concerning the differences in corticosteroid use between a diverse obese population and non-obese individuals. The main purpose of this study was to systematically explore the use of corticosteroids in obese subjects compared to non-obese controls. In addition, we also explored self-reported marked weight gain within obese subjects. Methods: Two hundred sevent...
Source: International Journal of Medical Sciences - Category: Biomedical Science Tags: Int J Med Sci Source Type: research
Conclusion: To address the many challenges posed by EDCs, we argue that Africans should take the lead in prioritization and evaluation of environmental hazards, including EDCs. We recommend the institution of education and training programs for chemical users, adoption of the precautionary principle, establishment of biomonitoring programs, and funding of community-based epidemiology and wildlife research programs led and funded by African institutes and private companies. https://doi.org/10.1289/EHP1774 Received: 16 February 2017 Revised: 22 May 2017 Accepted: 24 May 2017 Published: 22 August 2017 Address correspond...
Source: EHP Research - Category: Environmental Health Authors: Tags: Commentary Source Type: research
Hypertension carries a large societal burden. Obesity is known as a risk factor for hypertension. However, little is known as to whether weight loss interventions reduce the risk of hypertension-related advers...
Source: BMC Medicine - Category: Internal Medicine Authors: Tags: Research article Source Type: research
By Kelly Young Edited by David G. Fairchild, MD, MPH The American College of Obstetricians and Gynecologists offers several recommendations for managing obesity during adolescence. Among …
Source: Physician's First Watch current issue - Category: Primary Care Source Type: news
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