Opioid Overdoses and Deaths Flooding U.S. Hospitals

FRIDAY, Aug. 11, 2017 -- There's been a sharp rise in opioid-related admissions and deaths in hospital intensive care units across the United States, a new study finds. Opioids are pain medications, such as oxycodone (OxyContin, Percocet) and...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news

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Opioid use has reached epidemic proportions over the past decade, becoming one of America’s highest-priority public health issues. With opioid abuse spiraling out of control, lawmakers, regulators, and health professionals are scrambling to better understand key drivers of this issue and develop an effective action plan. Although the devastating impact of opioids on families and communities is well known, less focus has been given to how it affects the workplace and the role that employers and health care plan sponsors can play in combating it. Opioids’ impact on America’s workforce Opioid use is surging ...
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Policy Pain Management Public Health & Source Type: blogs
As a physician licensed to prescribe narcotics, I am legally   permitted to prescribe the powerful opioid methadone (also known by the brand name Dolophine  ) to my patients suffering from severe, intractable pain that hasn ’t been adequately controlled by other, less powerful pain killers. Most patients I encounter who might fall into that category are likely to be terminal cancer patients. I’ve often wondered why I am approved to prescribe methadone to my patients as a treatment for pain, but I am not allowed to prescribe methadone to taper my patients off of a physical dependence the...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
This article elucidates current pharmacologic options regarding analgesia in the emergency setting, with some possible future options.
Source: Current Emergency and Hospital Medicine Reports - Category: Emergency Medicine Source Type: research
Even as public opinion shifts in favor of marijuana legalization, withsixtypercent of Americans supporting broad legalization andninety percent supporting medical use, Attorney General Jeff Sessions and the Department of Justice (DOJ) continue to stonewall efforts to expand availability of cannabis and cannabis-derived treatments for medical research.Intestimony to a Senate Appropriations subcommittee in April, Sessions argued that althoughrecentstudies have shown that access to medical marijuana reduces opioid overdose deaths, the evidence to support expanding access is still insufficient.This is simply untrue. While DOJ ...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
The increased use of opioid pain medications in North America in the last 2 decades has given rise an epidemic of addictions, overdoses and deaths, to which both the US and Canadian governments have enacted strategies to help combat these crises [1-3]. While these strategies develop multiple interventions to curb opioid use, a common target is to reduce physician opioid prescribing. Many patients may receive their first dose of opioid in the Emergency Department (ED), and recent studies show that there has been a steady increase in opioid prescribing in US EDs to adults (relative increase of 49% from 2001 to 2010) [4, 5].
Source: The American Journal of Emergency Medicine - Category: Emergency Medicine Authors: Tags: Correspondence Source Type: research
Publication date: 2018Source: Toxicology Reports, Volume 5Author(s): Al Giwa, Edwin OeyAbstractTricyclic antidepressants (TCAs) were first approved by the Food and Drug Administration (FDA) for use as antidepressants in the 1950s. Although their function as an antidepressant in the U.S. has largely been replaced by newer and safer alternatives, they are still prescribed for various conditions, including chronic pain and intractable depression. We will discuss a case of a TCA overdose presenting with generalized tonic-clonic seizures and multiple recurrent cardiac arrests. This is a case of a 34 year-old female who was brou...
Source: Toxicology Reports - Category: Toxicology Source Type: research
Publication date: July 2018Source: Journal of Emergency Nursing, Volume 44, Issue 4Author(s): Daria L. Waszak, Ann M. Mitchell, Dianxu Ren, Laura A. FennimoreAbstractBackgroundThe opioid crisis continues to take an unprecedented number of lives and is the top cause of injury death in the United States. The emergency department is a setting where patients with pain seek care and may be prescribed an opioid, yet many patients do not receive evidence-based education about taking their opioid safely. Like many communities across the country, Allegheny County, Pennsylvania, has experienced an increased rate of opioid overdoses;...
Source: Journal of Emergency Nursing - Category: Nursing Source Type: research
ConclusionPrescription opioid shopping is not independently associated with increased risk of overdose events.
Source: Annals of Emergency Medicine - Category: Emergency Medicine Source Type: research
In this study, a sensitive, rapid and specific LC–MS/MS method for quantification of PX, VX and OH-VX in the plasma of tumor bearing mouse was developed and validated. After protein precipitation, all the analytes were separated on an Agilent ZORBAX Extend-C18 HPLC column (2.1 × 100 mm, 3.5 μm) with gradient elution. The analytes were detected by an electrospray negative ionization mass spectrometry in the multiple reaction monitoring mode. The transition m/z 369.0 → 119.0, m/z 312.9 → 117.9, m/z 329.0 → 196.0, and m/z 307.1 → 161.3 were used for monitoring PX, V...
Source: Journal of Pharmaceutical and Biomedical Analysis - Category: Drugs & Pharmacology Source Type: research
Publication date: May–June 2018Source: EXPLORE, Volume 14, Issue 3Author(s): Heather Tick, Arya Nielsen, Kenneth R. Pelletier, Robert Bonakdar, Samantha Simmons, Ronald Glick, Emily Ratner, Russell L. Lemmon, Peter Wayne, Veronica Zador, The Pain Task Force of the Academic Consortium for Integrative Medicine and HealthABSTRACTMedical pain management is in crisis; from the pervasiveness of pain to inadequate pain treatment, from the escalation of prescription opioids to an epidemic in addiction, diversion and overdose deaths. The rising costs of pain care and managing adverse effects of that care have prompted action ...
Source: EXPLORE: The Journal of Science and Healing - Category: Complementary Medicine Source Type: research
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