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Singing May Be Good Medicine for Parkinson's Patients

FRIDAY, Aug. 11, 2017 -- Singing? To benefit people with Parkinson's disease? It just may help, a researcher says. " We're not trying to make them better singers, but to help them strengthen the muscles that control swallowing and respiratory...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news

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Dominik Frentzel, Grigorij Judanin, Olga Borozdina, Jochen Klucken, J ürgen Winkler, Johannes C. M. Schlachetzki
Source: Frontiers in Neurology - Category: Neurology Source Type: research
This article is protected by copyright. All rights reserved.
Source: Journal of Neurochemistry - Category: Neurology Authors: Tags: Original Article Source Type: research
Authors: Lejko Zupanc T, Logar M Abstract A 21-year-old man with Wolff-Parkinson-White syndrome presented to the authors' hospital with ventricular fibrillation. Coronary angiography failed to demonstrate coronary stenosis, but temporary mechanical circulatory support resolved the ventricular fibrillation and the patient was extubated eight days later. On the next day, however, he had to be re-intubated with symptoms of congestive heart failure. Echocardiography revealed new severe mitral regurgitation and a mobile mass, while emergency surgery revealed a posteromedial papillary muscle rupture (PMR). The mitral reg...
Source: Journal of Heart Valve Disease - Category: Cardiology Tags: J Heart Valve Dis Source Type: research
CONCLUSION: This pilot study suggests that DT performance with a secondary motor task is worse in GBA-PD than in iPD patients. This finding may be associated with the known enhanced motor and cognitive deficits in GBA-PD compared to iPD and should motivate further studies. PMID: 28819579 [PubMed]
Source: Parkinsons Disease - Category: Neurology Tags: Parkinsons Dis Source Type: research
Publication date: 14 September 2017 Source:Neuroscience Letters, Volume 657 Author(s): Tao He, Jie Wang, Xiaoli Wang, Wenshuai Deng, Hong Jiang, Junxia Xie, Peng Sun Recent years, several case-control studies reported that two polymorphisms (rs947211 and 1572913) within the PARK16 locus were associated with the Parkinson's disease (PD). However, the results were still controversial. Herein, we conducted a comprehensive meta-analysis to estimate the associations between two polymorphisms and PD. Seven databases (PubMed, Google Scholar, EMBASE, Web of Science, CNKI (China National Knowledge Infrastructure), VIP and Wanfang)...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
Authors: Kianirad Y, Simuni T Abstract INTRODUCTION: Parkinson's disease psychosis (PDP) may develop in up to 60% of Parkinson's patients and is associated with increased morbidity and mortality. It also correlates with depression and dementia, and can contribute to caregiver stress and burnout. Pimavanserin is the first FDA approved drug for the treatment of hallucinations and delusions associated with PDP. Areas covered: For this review, a MEDLINE literature search (via PubMed) and information provided by ACADIA Pharmaceuticals were used. References of our search results were screened for additional studies. The ...
Source: Expert Review of Clinical Pharmacology - Category: Drugs & Pharmacology Tags: Expert Rev Clin Pharmacol Source Type: research
Conclusion : The present study demonstrated that LWDH-WE protects motor neurons against SMN deficiency-induced neurodegeneration, and it also improves the muscle strength of SMA-like mice, suggesting the potential benefits of LWDH-WE as a complementary prescription for SMN deficiency-related diseases. Graphical abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research
Authors: Yang JH, Wang YQ, Ye SQ, Cheng YG, Chen Y, Feng XZ Abstract OBJECTIVE: To compare the effects of group-based and individual-based Tai Chi training on nonmotor symptoms in patients with mild to moderate Parkinson's disease. DESIGN: Randomized controlled pilot study. METHODS: 36 community-dwelling patients with Parkinson's disease (PD) were randomly assigned to either group-based training group (n = 19) or individual-based group (n = 17). Both groups received same content of Tai Chi training 3 times a week for 13 weeks. Participants were also asked to perform home exercises daily. The Non-Motor Sympt...
Source: Parkinsons Disease - Category: Neurology Tags: Parkinsons Dis Source Type: research
Conclusions: In this study, we found no evidence that exposure to air pollution is a risk factor for PD in men. https://doi.org/10.1289/EHP259 Received: 01 April 2016 Revised: 07 November 2016 Accepted: 10 November 2016 Published: 18 August 2017 Address correspondence to N. Palacios, Dept. of Public Health, University of Massachusetts, Lowell; Lowell, Massachusetts. Telephone: 617-304-4254. Email: natalia_palacios@uml.edu Statistical analysis was done by N.P. and K.C.F. The authors declare they have no actual or potential competing financial interests. Note to readers with disabilities: EHP strives to ensu...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
Authors: Hattori N, Arano T, Hatano T, Mori A, Imai Y Abstract Parkinson's disease (PD) is a common neurodegenerative disorder, with ageing being a major risk factor. Accordingly, estimates predict an increasing number of PD patients due to our expanding life span. Consequently, developing a true disease-modifying therapy is necessary. In this regard, monogenic PD offers a suitable means for determining pathogenesis. Among monogenic forms of PD, mitochondrial dysfunction may be a major cause and is also likely to be involved in sporadic PD. Thus, mitochondrial impairment may be a common pathway. Recently, mitochond...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
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