Metal-catalyzed electrochemical diazidation of alkenes

Metal-catalyzed electrochemical diazidation of alkenesByNiankai Fu,Gregory S. Sauer,Ambarneil Saha,Aaron Loo,Song LinScience11 Aug 2017 : 575-579Electrochemical oxidation underlies a broadly applicable method to place nitrogen substituents on two adjacent carbons.Adjacent carbon-nitrogen bonds often appear in chemical compounds of pharmaceutical interest. Fuet al. developed a versatile method to form these bonds by pairing manganese catalysis with electrochemical azide oxidation in the presence of olefins. A major advantage of the electrochemical approach is the tunable precision of its oxidizing power, which leaves other sensitive substituents such as alcohols and aldehydes intact.

Source: Organometallic Current - August 11, 2017 Category: Chemistry Tags: Azidation C-N Bond Forming Electrochemical Mn catalyzed Source Type: blogs