PEGylation of Lumbrokinase improves pharmacokinetic profile and enhances anti ‑thrombotic effect in a rat carotid artery thrombosis model.

In conclusion, injectable PEGylated LK with prolonged half-life and enhanced anti‑thrombotic effect is a potential anti‑thrombotic agent for long‑acting treatment of the thrombus diseases. PMID: 28791355 [PubMed - as supplied by publisher]
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research