Different Exposures to Risk Factors Do Not Explain the Inverse Relationship of Occurrence Between Cancer and Neurodegenerative Diseases: An Italian Nested Case-control Study.
Different Exposures to Risk Factors Do Not Explain the Inverse Relationship of Occurrence Between Cancer and Neurodegenerative Diseases: An Italian Nested Case-control Study. Alzheimer Dis Assoc Disord. 2017 Aug 08;: Authors: Prinelli F, Adorni F, Leite MLC, Pettenati C, Russo A, Di Santo S, Musicco M Abstract Several studies reported that cancer is less frequent in persons with Alzheimer's and Parkinson's Diseases (AD/PD) and vice-versa. We evaluated whether a different distribution of known nongenetic risk factors for cancer and AD/PD, might explain their inverse relationship of occurrence. We nested 2 case-control studies in a subsample of a large cohort of 1,000,000 resident in Lombardy Region in Italy (n=1515), followed-up for cancer and AD/PD occurrence since 1991 until 2012. Conditional logistic regression was performed to determine the odds ratios (OR) and 95% confidence intervals (CI) of AD/PD in subjects with and without cancer and the risk of cancer in those with and without AD/PD. A total of 54 incident cases of AD/PD and 347 cancer cases were matched with 216 and 667 controls, respectively. After controlling for low education, obesity, history of hypertension, diabetes, dyslipidemia, physical activity, smoking habit, alcohol consumption, and dietary habit, cancer was found inversely associated with the risk of AD/PD (OR, 0.66; 95% CI, 0.32-1.38), and the risk of cancer in AD/PD was similarly reduced (OR, 0.42; 95% CI, 0.20-0.91). Different ex...
Conclusion: The results of our study suggest thatAnisomeles malabarica has potential anti-diabetic activity in STZ induced diabetic rats.Cell Physiol Biochem 2017;43:1689 –1702
The incidence of mouth and throat cancers caused by the human papillomavirus in men has now surpassed the incidence of HPV-related cervical cancers in women.
(Reuters) - A new therapy for a type of lymphoma developed by Kite Pharma, which was acquired by Gilead Sciences Inc, won U.S. approval on Wednesday, marking the second approval for this potentially revolutionary approach to fighting cancer.
U.S. regulators approve 2nd gene therapy for blood cancer, 1st one for adults
The Food and Drug Administration approved a second version of a groundbreaking treatment Wednesday that genetically alters patients' cells to attack cancer — this time, to fight aggressive non-Hodgkin lymphoma. The treatment is for adults with certain types of large B-cell lymphoma who have not responded to or who have relapsed after at least two other […]Related:Josh Gordon, new director of the National Institute of Mental Health, weighs its futureA 2-year-old’s kidney transplant was put on hold — after his donor father’s probation violationThe mother jailed for refusing to vaccinate he...
WASHINGTON (Reuters) - Novo Nordisk A/S's new diabetes drug semaglutide is effective, reasonably safe and should be approved, an advisory panel to the U.S. Food and Drug Administration concluded on Wednesday.
Penn State College of Medicine researchers found that textured implants might be more dangerous than smooth implants. They are supposedly more likely to cause breast cancer.
Researchers at the University of Ottawa found five times the amount of cancer-causing chemicals on the skin of firefighters - a higher figure than previously thought - but a shower cut their risk.
A recent study relates future risk to current risk for advanced colorectal cancer. Dr Kerr suggests adding genetic testing to further improve diagnosis.Medscape Oncology
New data from the CDC's National Center for Health Statistics show less than half of US adults with hypertension have their blood pressure under control, basically unchanged since 2010.Medscape Medical News
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