Opioid Overdoses & Deaths Flooding U.S. Hospitals
Medical costs jumped more than $30,000 per patient in less than 10 years, study finds
The suit claims drug companies played a role in the skyrocketing number of opioid overdoses
This study compares the effectiveness and appropriateness of naloxone administration between BLS and ALS providers. METHODS: All Vermont, New Hampshire, and Maine EMS patient encounters between April 1, 2014 and December 31, 2016 where naloxone was administered were examined and 3,219 patients were identified. The proportion of successful reversals of opioid overdose, based on improvement in the Glasgow Coma Scale (GCS), respiratory rate (RR), and provider global assessment (GA) of response to medication was compared between BLS and ALS providers using a Chi-Squared statistic, Fisher's exact or Wilcoxon rank-sum test. ...
BACKGROUND: A staggering number of Americans are dying from overdoses attributed to prescription opioid medications (POMs). In response, states are creating policies related to POM harm reduction strategies, overdose prevention, and alternative therapies f...
This article is protected by copyright. All rights reserved. All organisms must strike a delicate balance between acquiring the essential nutrient iron and avoiding its toxicity. We demonstrate that the human fungal pathogen Candida albicans has evolved a sophisticated, robust iron acquisition system that can assemble different sets of high‐affinity iron transporters according to iron availability. This trait especially suits the commensal‐pathogenic lifestyle of C. albicans that traverses host niches with drastically different levels of iron supply.
ConclusionBlockage of IL-33/ST2 axis reduces APAP-mediated organ injury by dampening liver chemokine release and activation of resident and infiltrating liver non-parenchymal cells.
More than 63,000 people died from a drug overdose last year – that’s more than the number of deaths caused by AIDS in 1995, according to data from the Centers for Disease Control and Prevention. Between 2015 and 2016, the number of people who died from a drug overdose involving illicitly-manufactured fentanyl, a synthetic opioid, more than doubled. Available data shows that heroin contaminated with fentanyl has largely driven the recent increases in opioid-related overdose deaths, Dr. Deborah Dowell from the CDC wrote in an article published this week in JAMA. Get the full story at our sister site, Dr...
Condition: Drug Overdose Interventions: Device: Syringe and needle; Device: Intranasal mucosal atomization device; Device: Nasal spray Sponsor: State University of New York - Upstate Medical University Completed
After leaving the hospital one evening, two residents came upon an opioid overdose situation. What happened next underscores the importance of, and challenges with, obtaining life-saving naloxone.Medscape Public Health
Police Executive Research Forum. 09/2017 This 92-page report summarizes the epidemic of overdoses by persons addicted to opioid drugs, and what was learned at a national conference held in April 2017. The Police Executive Research Forum focuses on the opioid crisis because despite the work that police and other agencies are doing, the epidemic is continuing to worsen. New concepts in the report include the use of synthetic opioids fentanyl and carfentanil, ways in which police agencies and their partners are developing ways to share information, and how police officers are saving lives with naloxone. (PDF)
To investigate the epidemiology and outcomes of cardiac arrests associated with opioid overdoses. Recent data suggest that drug overdoses are responsible for more deaths than motor vehicle crashes or firearms in the United States each year, with opioids being involved in majority of drug overdose deaths. Despite the potential for opioids to cause cardiac arrest, few studies have examined this association.