Recent advances in Vertebral Augmentation for the treatment of Vertebral body compression fractures

AbstractPurpose of ReviewOsteoporotic and pathologic vertebral compression fractures (VCFs) result in significant pain, reduced quality of life, and patient morbidity. Vertebral augmentation procedures (VAPs), which include vertebroplasty and kyphoplasty, have been extensively studied. Here, we review the evidence for the effectiveness of these techniques with an emphasis on recent clinical trials.Recent FindingsThere has been controversy regarding the effectiveness of VAPs in the treatment of painful VCFs. Recent high-quality clinical trials have demonstrated that with proper patient selection, which includes identification of (1) pain referable to a fracture, (2) acute or subacute fracture (less than 6  weeks), and (3) evidence of bone edema or intravertebral clefts on magnetic resonance imaging or high radiotracer uptake on bone scintigraphy, patients are highly likely to achieve significant improvements in long-term pain control and reduced pain-related disability with low procedural risk. Both vertebroplasty and kyphoplasty are effective VAPs, and no high-quality, recent study has found a substantial difference in the relative effectiveness of these techniques.SummaryVAPs are safe and effective in the management of acute, painful osteoporotic, and pathologic VCFs given appropriate clinical and imaging-based patient selection. Developing evidence suggests a role for VAPs in the management of painful chronic osteoporotic fractures, and as part of a multimodal approach...
Source: Current Physical Medicine and Rehabilitation Reports - Category: Rehabilitation Source Type: research

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Source: Pain - Category: Anesthesiology Tags: Research Paper Source Type: research
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Source: Pain - Category: Anesthesiology Tags: Clinical Note Source Type: research
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Source: Pain - Category: Anesthesiology Tags: Research Paper Source Type: research
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Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: Journal of Developmental and Physical Disabilities - Category: Disability Source Type: research
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Source: SafetyLit - Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news
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Source: The Clinical Journal of Pain - Category: Anesthesiology Tags: Special Topic Series: Approach to Physical Activity in Pain: From Theory to the Lab, From Clinic to the Patient Source Type: research
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Source: The Clinical Journal of Pain - Category: Anesthesiology Tags: Special Topic Series: Approach to Physical Activity in Pain: From Theory to the Lab, From Clinic to the Patient Source Type: research
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Source: The Clinical Journal of Pain - Category: Anesthesiology Tags: Original Articles Source Type: research
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Source: Neurological Sciences - Category: Neurology Source Type: research
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