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Nurse-led screening in GP practices boosts early lung cancer and COPD detection

A nurse-led screening programme in Liverpool is preventing around two cases of lung cancer a month across a dozen practices and driving up early detection of COPD, researchers have found.
Source: GP Online News - Category: Primary Care Tags: 15.8 Respiratory Problems Source Type: news

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BackgroundThe impact of chronic obstructive pulmonary disease (COPD) severity on survival after curative resection of early‐stage lung cancer (NSCLC) has not been sufficiently elucidated. MethodsWe retrospectively reviewed 250 consecutive patients who underwent lobectomy with lymph nodal dissection for pathological stage I–II NSCLC. ResultsAmong the COPD patients, 28 were classified as Global Initiative for Chronic Obstructive Lung Disease (GOLD) 1, 21 as GOLD 2, and one as GOLD 3. The cumulative overall survival (OS) of the non‐COPD, GOLD 1, and GOLD 2–3 groups at five years was 90.7%, 85.7%, and 55...
Source: Thoracic Cancer - Category: Cancer & Oncology Authors: Tags: ORIGINAL ARTICLE Source Type: research
We explored whether the proteomic analysis of exhaled breath condensate (EBC) may provide biomarkers for noninvasive screening for the early detection of lung cancer (LC). EBC was collected from 192 individuals [49 control (C), 49 risk factor-smoking (S), 46 chronic obstructive pulmonary disease (COPD) and 48 LC]. With the use of liquid chromatography and tandem mass spectrometry, 348 different proteins with a different pattern among the four groups were identified in EBC samples. Significantly more proteins were identified in the EBC from LC compared with other groups (C: 12.4 ± 1.3; S: 15.3 ± 1; COPD: 14 &p...
Source: AJP: Lung Cellular and Molecular Physiology - Category: Respiratory Medicine Authors: Tags: RESEARCH ARTICLE Source Type: research
Author Affiliations open 1Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada 2Swiss Tropical and Public Health Institute, Basel, Switzerland 3University of Basel, Basel, Switzerland 4Institute for Risk Assessment Sciences, Utrecht University, Utrecht, Netherlands 5MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK 6National Human Genome Research Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA 7University Medical Center Groningen, Gron...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
Conclusions: Peroral arsenic has little effect on local airway immune responses to bacteria but compromises respiratory epithelial barrier integrity, increasing systemic translocation of inhaled pathogens and small molecules. https://doi.org/10.1289/EHP1878 Received: 09 March 2017 Revised: 14 August 2017 Accepted: 16 August 2017 Published: 28 September 2017 Address correspondence to M.B. Fessler, National Institute of Environmental Health Sciences, 111 T.W. Alexander Dr., P.O. Box 12233, Maildrop D2-01, Research Triangle Park, NC 27709 USA. Telephone: (919) 541-3701. Email: fesslerm@niehs.nih.gov *Current address: UN...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
2 –3 October 2017, McLean, United States
Source: Scientific and Medical Events on Global Events List - Category: Science Source Type: events
Abstract BACKGROUND: Patients with lung cancer are known to be at increased risk for venous thromboembolism (VTE). Venous thromboembolism is associated with increased risk for early mortality. However, there have been no studies performing a comprehensive assessment of risk factors for VTE or early mortality in lung cancer patients undergoing systemic chemotherapy in a global real-world setting. MATERIALS AND METHODS: CANTARISK is a prospective, global, noninterventional cohort study including patients with lung cancer initiating a new cancer therapy. Clinical data were collected until 6-month follow-up. The ...
Source: The Oncologist - Category: Cancer & Oncology Authors: Tags: Oncologist Source Type: research
CONCLUSIONS: In patients with COPD, Th1 cells populations were expanded in both lungs and tumors microenvironments, and the presence of COPD was associated with longer progression free interval in patients treated with ICIs. This has implications for understanding the immune mediators of COPD and for developing novel therapies for NSCLC. PMID: 28934595 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - Category: Respiratory Medicine Authors: Tags: Am J Respir Crit Care Med Source Type: research
Conclusions Knowing that the incidence of lung cancer increased globally in both male and female, the relatively lower male to female ratio when compared with other studies, may reflect at least an increasing in the lung cancer rates among female. Smoking still remains the major risk factor in pathogenesis of primary lung cancer. COPD could be considered an important respiratory disorder that tied to bronchogenic carcinoma risk. Interestingly, the incidence of adenocarcinoma surpassed that of squamous cell carcinoma. Unfortunately, presentation of the patient at later stages of illness was common.
Source: Egyptian Journal of Chest Diseases and Tuberculosis - Category: Respiratory Medicine Source Type: research
Publication date: October 2017 Source:Hospital Medicine Clinics, Volume 6, Issue 4 Author(s): Pouria Kashkouli, Kimberly Ann HardinTeaser Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in the United States. Patients with COPD have a significant need for palliative care interventions. Symptom burden in this population is as high or higher, and present for a longer period of time, as in lung cancer. There is both psychological and physical decline. Individuals with COPD have frequent hospitalizations that often result in intensive care unit admission. Compared with patient with lung cancer,...
Source: Hospital Medicine Clinics - Category: Internal Medicine Source Type: research
Conclusion The incidence of extrapulmonary cancer in patients with COPD was twice that of lung cancer; stages I–II of the 2009 GOLD classification and the PYI were significantly related to the onset of neoplasia.
Source: Revista Clinica Espanola - Category: Internal Medicine Source Type: research
More News: Cancer | Cancer & Oncology | Chronic Obstructive Pulmonary | Lung Cancer | Nurses | Nursing | Primary Care | Respiratory Medicine