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Opiate Addiction and Treatment Resources from the National Library of Medicine

In response to the growing heroin epidemic in the United States, the National Library of Medicine’s Specialized Information Services has created a portal to provide resources and information on prescribing, overdose, medication-assisted treatment, and recovery. According to the American Society of Addiction Medicine, addiction is defined as: “A primary, chronic disease of brain reward, motivation, memory and related circuitry. Dysfunction in these circuits leads to characteristic biological, psychological, social and spiritual manifestations. This is reflected in an individual pathologically pursuing reward and/or relief by substance use and other behaviors.” 1 The portal includes information for those addressing addiction: healthcare providers, educators, researchers, patients and families. Deaths from overdose have been steadily increasing nationwide, and from 2002 – 2015 there was a 2.8 fold increase in number of deaths from opioids. In Seattle and King County such deaths numbered 359 in 2016, according to the King County Medical Examiner’s Office. Understanding addiction and treatment is part of the picture, as well as chronic pain management, education, and support for families and those in recovery. Besides offering educational resources, some libraries have joined the front lines in preventing death from overdose. Public libraries around the country have trained their staff in the use of Naloxone, a nasal spray which reverses overdose f...
Source: Dragonfly - Category: Databases & Libraries Authors: Tags: News from NLM Public Health Source Type: news

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After years of investigation of McKesson Corp., led by a Denver-based Drug Enforcement Administration team, over the pharmaceutical giant's distribution of powerful opioid drugs in Colorado and elsewhere, DEA agents say they thought they had gathered enough evidence to warrant criminal charges, fines of more than $1 billion and blocking distribution of opioid pain pills from McKesson warehouses in Aurora and elsewhere. The DEA probe examined whether San Francisco-based McKesson (NYSE: MCK) failed…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Authors: Torres-Landa S, Kannan U, Guajardo I, Pickett-Blakely OE, Dempsey DT, Williams NN, Dumon KR Abstract Obesity is a spreading epidemic associated with significant morbidity and mortality with a prevalence of over 36% worldwide. In the face of a growing epidemic, increasing medical costs, and the disappointing limitations of medical and lifestyle modification bariatric surgery was found to consistently lead to significant weight loss and improvement in obesity-associated comorbidities when compared to non-surgical interventions. Bariatric procedures fall within three basic categories: restrictive procedures, ...
Source: Minerva Chirurgica - Category: Surgery Tags: Minerva Chir Source Type: research
Dissociation is a mental process, which produces a lack of connection in a person’s thoughts, memories, feelings, actions, or sense of identity. During the period of time when a person is dissociating, certain information is not associated with other information as it normally would be. For example, during a traumatic experience, a person may dissociate the memory of the place and circumstances of the trauma from his ongoing memory, resulting in a temporary mental escape from the fear and pain of the trauma and, in some cases, a memory gap surrounding the experience. Because this process can produce changes in memory...
Source: Psych Central - Category: Psychiatry Authors: Tags: Disorders Dissociation Dissociative General Personality Source Type: news
Authors: Parrino MW Abstract By all published accounts and federal government reports, the United States is experiencing a serious opioid use epidemic. Additional treatment resources are needed in order to provide access to evidence based medical care for untreated individuals with substance use disorders. The focus of this commentary is increasing access to more opioid treatment programs and overcoming the significant impediments, which block such efforts. PMID: 29244540 [PubMed - as supplied by publisher]
Source: Substance Use and Misuse - Category: Addiction Tags: Subst Use Misuse Source Type: research
In this study, we asked people in an open-ended way about their desire for longer life: Would you like to have more time? What age would you like to become? This was something more specific than asking about a preference for survival without reference to any length of time; about one's plans for the future; or whether people see the future as open or limited, as in studies of future time perspective. Our attempt was to discover whether there were preferred temporal spans with which older adults framed their futures and plans. The two-question series about extra years and desired age ("How old would you like to ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Authors: Mason BJ, Quello S, Shadan F Abstract INTRODUCTION: Alcohol misuse is the fifth leading risk factor for premature death and disability worldwide. Fewer than 10% of afflicted Americans receive pharmacological treatment for alcohol use disorder. Gabapentin is a calcium channel GABAergic modulator that is widely used for pain. Studies showing reduced drinking and decreased craving and alcohol-related disturbances in sleep and affect in the months following alcohol cessation suggest therapeutic potential for alcohol use disorder. Areas covered: Human laboratory and clinical studies assessing gabapentin for alc...
Source: Expert Opinion on Investigational Drugs - Category: Drugs & Pharmacology Tags: Expert Opin Investig Drugs Source Type: research
Authors: Phillips PK, Caldis MW, Hristov AD, Lee AS, Lucey MR Abstract The manufacture and consumption of alcohol are ubiquitous and as old as time. Alcohol use disorder (AUD) is defined as a problematic pattern of alcohol use leading to clinically significant impairment. The physical injuries that result from excessive alcohol consumption are varied including end-organ damage to liver (alcohol-associated liver disease or ALD), pancreas, brain and heart, and systemic consequences including several forms of cancer. Liver transplantation (LT) remains the treatment of last resort for life-threatening liver disease. LT...
Source: Minerva Gastroenterologica e Dietologica - Category: Gastroenterology Tags: Minerva Gastroenterol Dietol Source Type: research
Conclusion and Recommendations More intervention-based clinical trials are needed to provide a strong alternative candidate therapy for management of opiate use disorder. Buprenorphine, although a promising candidate, should be researched more regarding treatment retention and patient satisfaction before any conclusions can be made regarding its standard use for opiate substitution maintenance treatment of pregnant patients with opiate use disorder. Heroin-assisted treatment still cannot be considered in opiate addicts refractory to MMT; more data should be collected regarding efficacy in larger participant populations un...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Current Issue General Review buphernorphin heroin methadone opiate opiate addiction treatment withdrawal Source Type: research
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Source: Health Affairs Blog - Category: Health Management Authors: Tags: Following the ACA Medicaid and CHIP Public Health Essential Health Benefits Medicaid expansion opioid epidemic opioids Section 1115 Demonstration Waiver Substance Use Disorders Source Type: blogs
There are many steps that need to be taken to end an epidemic—including policy, medication, coverage and treatment expansion—and require physicians to take the lead in fighting for their patients. Leaders in Pennsylvania are on a mission to provide that help to both the people who are suffering in the opioid epidemics and the physicians who treat them. A standing order for naloxone Through a multiagency effort, Pennsylvania’s physician general Rachel Levine, MD, in October signed a statewide prescription for naloxone, making this lifesaving overdose reversal drug available to the entire population. ...
Source: AMA Wire - Category: Journals (General) Authors: Source Type: news
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