Chapter Forty-Seven Nonmotor Symptoms in Vascular and Other Secondary Parkinsonism

Publication date: 2017 Source:International Review of Neurobiology, Volume 134 Author(s): Oleg S. Levin, Achcha Sh. Chimagomedova, Natalia A. Skripkina, Elena A. Lyashenko, Olga V. Babkina Vascular parkinsonism (VP) is a relatively frequent variant of secondary parkinsonism caused by ischemic or hemorrhagic lesions of basal ganglia, midbrain, or their links with frontal cortex. According to different investigations, various forms of cerebrovascular disease cause 1%–15% of parkinsonism cases. Nonmotor symptoms are frequently found in VP and may negatively influence on quality of life. However, nonmotor symptoms such as hallucinations, orthostatic hypotension, REM-sleep behavior disorder, and anosmia are rarely revealed in VP, which may be noted to another diagnosis or mixed pathology. Clinical value of nonmotor symptoms in normal pressure hydrocephalus, toxic, and drug-induced parkinsonism is also discussed.
Source: International Review of Neurobiology - Category: Neuroscience Source Type: research