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How AI Robots Hunt New Drugs For Crippling Nerve Disease

ALS attacks and kills nerve cells controlling muscles, leading to weakness, paralysis and, ultimately, respiratory failure.
Source: Science - The Huffington Post - Category: Science Source Type: news

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Authors: Unnewehr M, Kolditz M, Windisch W, Schaaf B Abstract Biomarkers play an important role in the management of infectious pulmonary diseases, even though there is only limited evidence that biomarker-guided therapies are superior to clinical strategies.Well-established indications for the use of biomarkers are the guidance of the duration of antibiotic therapy in community-acquired pneumonia (CAP) by PCT, the decision against the use of antibiotics by CRP or PCT in ambulatory settings, and the evaluation of CAP treatment by CRP or PCT kinetics.In the prognostic assessment of CAP, the standard biomarkers of ac...
Source: Pneumologie - Category: Respiratory Medicine Tags: Pneumologie Source Type: research
This article is intended to facilitate differential diagnosis by a systematic description of relevant pathologies, notably with occupational etiology. Clinical findings of relevant diseases, i. e. of tuberculosis, chronic beryllium disease, sarcoidosis, lung cancer, malignant lymphoma, Epstein-Barr virus infection, and histoplasmosis are compared.Case history, imaging and laboratory tests have important diagnostic impact. But also invasive methods can be necessary in order to exclude and prove malignancy, infection or autoimmune disease. PMID: 29046010 [PubMed - as supplied by publisher]
Source: Pneumologie - Category: Respiratory Medicine Tags: Pneumologie Source Type: research
Conclusion Human beings who need to be out of hospital an invasive or non-invasive ventilation, it is difficult to decide for the ventilation and the right time to begin it. With the ventilation, they then connect a positive feeling of life. To enable a self-determined and active life to humans with invasive ventilation, it is important for health care providers to know the needs and to adapt to them individually. PMID: 29046009 [PubMed - as supplied by publisher]
Source: Pneumologie - Category: Respiratory Medicine Tags: Pneumologie Source Type: research
We report a case of a severe hemorrhagic shock in a 93-year old patient due to diagnostic thoracocentesis. PMID: 29046008 [PubMed - as supplied by publisher]
Source: Pneumologie - Category: Respiratory Medicine Tags: Pneumologie Source Type: research
Conclusions: This study shows that post-dilution online hemodiafiltration reduces all-cause and cardiovascular mortality compared to high-flux HD in an incident HD population.Am J Nephrol 2017;46:288 –297
Source: American Journal of Nephrology - Category: Neurology Source Type: research
Conclusions: Hyperuricemia is associated with increased risk of progression to ESRD in patients with CKD stages 3 and 4, but UALT does not ameliorate the risk, suggesting that the relationship is not causal.Am J Nephrol 2017;46:315 –322
Source: American Journal of Nephrology - Category: Neurology Source Type: research
Cerebrovasc Dis 2017;44(suppl 1):1-52
Source: Cerebrovascular Diseases - Category: Neurology Source Type: research
Cerebrovasc Dis 2017;44(suppl 1):I-II
Source: Cerebrovascular Diseases - Category: Neurology Source Type: research
61 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Am J Trop Med Hyg These pubmed results were generated on 2017/10/19PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Source: Am J Trop Med Hyg - Category: Infectious Diseases Tags: Report Source Type: research
CONCLUSION: The generated human monoclonal antibodies can be used to develop a potent immunotherapy that can be administrated for the post-transplantation patients to prevent the recurrence of HCV infection. Also, the monoclonal antibodies can be used to develop a vaccine against HCV. PMID: 29036810 [PubMed - as supplied by publisher]
Source: Human Antibodies - Category: Biochemistry Tags: Hum Antibodies Source Type: research
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