Dopamine plasma clearance is increased in piglets compared to neonates during continuous dopamine infusion

ConclusionOur results suggest that pharmacokinetic differences may explain the interspecific difference in required doses of dopamine infusion to increase blood pressure. This is important when translating the results obtained in piglet models to treating neonatal hypotension with dopamine.This article is protected by copyright. All rights reserved.

Source: Acta Paediatrica - August 10, 2017 Category: Pediatrics Authors: Martin B Rasmussen, Jan Bert Gramsbergen, Vibeke R Eriksen, Gorm Greisen Tags: Regular Article Source Type: research