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Spatial Characteristics of Jaw Movements During Chewing in Children with Cerebral Palsy: A Pilot Study

This study compared jaw motion between children with cerebral palsy (CP) and their typically-developing (TD) peers during chewing. The jaw movements of 11 children with spastic CP (GMFCS levels II –V) all of whom were exclusively oral feeders with no reported clinical issues with feeding [mean age = 7.49 (2.30) years; 7 males, 4 females] and 11 age- and sex-matched TD peers [mean age = 7.54 (2.35) years] were recorded using optical motion capture. Participants chewed five trials of thre e different consistencies, including puree, mechanical soft, and solid. For each chewing sequence, the path distance (total amount of distance traveled by the jaw), average jaw speed, and working space (total 3-dimensional size of the jaw movements during chewing) were calculated. The CP group had g reater path distances for mechanical soft and solids (p 
Source: Dysphagia - Category: Speech-Language Pathology Source Type: research

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A robotic exoskeleton attached to the lower leg may someday help kids with cerebral palsy maintain the ability to walk.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news
Half of children with cerebral palsy lose the ability to walk by adulthood. A new exoskeleton may improve their walking more than corrective surgery
Source: New Scientist - Health - Category: Consumer Health News Source Type: research
Gaucher disease (GD) is the most common type of lysosomal storage disease, with type 2 being the most severe subtype. Type 2 GD patients suffer significant progressive neurological impairment, including spasticity, opisthotonus, seizure, and apnea. The recently developed enzyme replacement therapy (ERT) has shown therapeutic benefit for GD. However, as the enzymes do not cross the blood-brain barrier, ERT does not ameliorate neurological impairment in GD. Intrathecal baclofen therapy (IBT) is indicated for spastic neurological diseases, such as cerebral palsy, and studies have shown its therapeutic benefit in improving sev...
Source: Pediatric Neurosurgery - Category: Neurosurgery Source Type: research
The ability to walk contributes considerably to physical health and overall well-being, particularly in children with motor disability, and is therefore prioritized as a rehabilitation goal. However, half of ambulatory children with cerebral palsy (CP), the most prevalent childhood movement disorder, cease to walk in adulthood. Robotic gait trainers have shown positive outcomes in initial studies, but these clinic-based systems are limited to short-term programs of insufficient length to maintain improved function in a lifelong disability such as CP. Sophisticated wearable exoskeletons are now available, but their utility ...
Source: Science Translational Medicine - Category: Biomedical Science Authors: Tags: Research Articles Source Type: research
General movements are present from early fetal life to 3 to 5 months corrected age. Atypical general movements, especially in the last, so‐called fidgety general movement phase, are predictive of cerebral palsy (CP). This review updates knowledge on the neural substrate and clinical significance of typical and atypical general movements. Typical general movements are primarily characterized by complexity and variation. Presumably these core characteristics are initially induced by modulating activity of the cortical subplate. When the subplate gradually dissolves between 3 months before term and 3 months corrected age th...
Source: Developmental Medicine and Child Neurology - Category: Child Development Authors: Tags: Review Source Type: research
This commentary is on the original article by Meehan et al.
Source: Developmental Medicine and Child Neurology - Category: Child Development Authors: Tags: Commentary Source Type: research
ConclusionPostnatally occurring hypoxic insults promote remodeling of the dopaminergic system resulting in increased intracellular sequestering of this monoamine. That sequestered dopamine can be released using the psychostimulant d-amphetamine, which did not promote a conditioned place preference any greater than was observed in non-hypoxic littermate controls.
Source: Sleep and Breathing - Category: Respiratory Medicine Source Type: research
(University of Adelaide) A new international research group has been established to investigate the underlying genetic causes of cerebral palsy, spurred on by the discoveries of University of Adelaide researchers.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
This commentary is on the systematic reviews by Reedman et al.
Source: Developmental Medicine and Child Neurology - Category: Child Development Authors: Tags: Commentary Source Type: research
Abstract PURPOSE: The purpose of this study is to evaluate effects of a running intervention on running ability and participation in children with cerebral palsy. MATERIALS AND METHOD: Children with cerebral palsy (9-18 years) with Gross Motor Function Classification System levels I-III were randomly assigned to a 12-week running intervention or usual care. Primary outcomes included improvement in running ability (assessed by Goal Attainment Scaling, high level mobility (assessed by the High-Level Mobility Assessment Tool) and participation (assessed by the Participation and Environment Measure for Children a...
Source: Disability and Rehabilitation - Category: Rehabilitation Authors: Tags: Disabil Rehabil Source Type: research
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