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The effects of intranasal dexmedetomidine premedication in children: a systematic review and meta-analysis

ConclusionsIntranasal dexmedetomidine provided more satisfactory sedation at parent separation and reduced the need for rescue analgesics and the incidence of nasal irritation and postoperative nausea and vomiting when compared with other premedication treatments.
Source: Canadian Journal of Anesthesia - Category: Anesthesiology Source Type: research

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Conclusions: Assessment of pain using positive word like comfort decreases its incidence with no effect on its severity when measured by comfort score and also affects patient's postsurgical perceptions.
Source: Saudi Journal of Anaesthesia - Category: Anesthesiology Authors: Source Type: research
We report a case of a 31-year-old female patient suffering from MS, who underwent gynecological surgery under general anesthesia with sevoflurane, fentanyl, and rocuronium which was successfully reversed with sugammadex. Neuromuscular transmission (NMT) monitoring was used to guide the intraoperative doses of rocuronium and also the reversal of NMB by the use of sugammadex to ensure a safe tracheal extubation. In addition, delivered volatile was titrated according to anesthetic depth monitoring (Bispectral Index) while esophageal temperature was also monitored for the maintenance of normothermia. Postoperatively, a multimo...
Source: Saudi Journal of Anaesthesia - Category: Anesthesiology Authors: Source Type: research
The induction of anesthesia is known to be the most stressful part of the day of surgery for the child. Non-pharmacologic intervention is a field of great interest. The aims of this prospective randomized study were to evaluate if (1). A preoperative visit to the operating theatre would attenuate the anxiety of the child on the day of surgery. (2). A preoperative visit to the operating theatre would attenuate the anxiety of the parent on the day of surgery.
Source: Journal of Pediatric Nursing - Category: Nursing Authors: Source Type: research
Abstract INTRODUCTION: The aim of this study was to detect the effect of 1 μg/kg of oral dexmedetomidine (DEX) as premedication among children undergoing dental procedures. MATERIALS AND METHODS: The study involved 100 children between 2 and 6 years of age, ASA I, who underwent full-mouth dental rehabilitation. The DEX group (n = 50) received 1 μg/kg DEX in apple juice, and the control group (n = 50) received only apple juice. The patients' scores on the Ramsay Sedation Scale (RSS), parental separation anxiety scale, mask acceptance scale, and pediatric anesthesia emergence delirium scale ...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
If dreams were movies, they wouldn’t make a dime. They’re often banal, frequently fleeting and they’re screened for an audience of just one. As for the storyline? You’re in a supermarket, only it’s also Yankee Stadium, shopping with your second-grade teacher until she turns into Ruth Bader Ginsburg. Then you both shoot a bear in the cereal aisle. Somebody call rewrite. But dreams are vastly more complex than that, and if you’ve got a theory that explains them, have at it. The ancient Egyptians thought of dreams as simply a different form of seeing, with trained dreamers serving as seers ...
Source: TIME.com: Top Science and Health Stories - Category: Consumer Health News Authors: Tags: Uncategorized behavior dreams Freud health Jung mind psychology sleep the brain Source Type: news
In conclusion, the effects of pre‐operative information on peri‐operative anxiety and other outcomes were affected little by format or timing.
Source: Anaesthesia - Category: Anesthesiology Authors: Tags: Review Article Source Type: research
CONCLUSION: Continuous regional anaesthesia provides analgesic benefit for up to 1 month after surgery, but did not influence PPSP at 6 months. Better pain control at 1 month was associated with reduced PPSP. Patients with higher expectations from surgery, enhanced basal inflammation and a pessimistic outlook are more prone to develop PPSP. TRIAL REGISTRATION: Clinicaltrials.gov identifier: NCT02147730
Source: European Journal of Anaesthesiology - Category: Anesthesiology Tags: Pain Source Type: research
Conclusions: These data demonstrate the critical role of neural AR in courtship vocalizations and raises the possibility that the vulnerability of this signaling pathway to exposure to endocrine disrupters may be detrimental for courtship communication and mating in several species. https://doi.org/10.1289/EHP1443 Received: 01 December 2016 Revised: 08 June 2017 Accepted: 09 June 2017 Published: 01 September 2017 Address correspondence to S. Mhaouty-Kodja, INSERM U1130, CNRS UMR 8246, Université P. &M. Curie, 7 quai St Bernard, Bât A 3ème étage 75005, Paris, France. Phone: +331 44 27 91...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
BackgroundThe purpose of this study was to investigate the association between dynamic thiol/disulphide homeostasis and occupational exposure to volatile anesthetic gases in operating theater personnel. Decreased blood thiol levels and raised blood disulphide levels serve as biomarkers of oxidative stress. MethodsWe included 65 subjects occupationally exposed and 55 unexposed healthy medical professionals into the study. A novel method enabled separate measurements of components involved in dynamic thiol/disulphide homeostasis (native thiol, disulphide, and total thiol). To control for the potential confounding effect on o...
Source: American Journal of Industrial Medicine - Category: Occupational Health Authors: Tags: RESEARCH ARTICLE Source Type: research
Peripheral intravenous (PIV) cannulation needed for pediatric procedural sedation (PPS) is a common source of stress for patients and families. The goal of this project is to investigate the perceived effectiveness of nitrous oxide (N2O) in reducing anxiety and pain associated with PIV cannulation for PPS by various stakeholders. N2O was used as an adjunct to local anesthesia and child life intervention to reduce the anxiety and pain associated with PIV placement before PPS. N2O use was at the discretion of physician.
Source: Journal of Radiology Nursing - Category: Radiology Authors: Source Type: research
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